Please use this identifier to cite or link to this item:
https://hdl.handle.net/10356/97497
Title: | Enantioselective intramolecular formal [2 + 4] annulation of acrylates and α,β-unsaturated imines catalyzed by amino acid derived phosphines | Authors: | Jin, Zhichao Yang, Ruojie Du, Yu Tiwari, Bhoopendra Ganguly, Rakesh Chi, Robin Yonggui |
Issue Date: | 2012 | Source: | Jin, Z., Yang, R., Du, Y., Tiwari, B., Ganguly, R., & Chi, Y. R. (2012). Enantioselective Intramolecular Formal [2 + 4] Annulation of Acrylates and α,β-Unsaturated Imines Catalyzed by Amino Acid Derived Phosphines. Organic Letters, 14(12), 3226-3229. | Series/Report no.: | Organic letters | Abstract: | The first chiral phosphine-catalyzed activation of acrylates for intramolecular formal [2 + 4] reactions with unsaturated imines is described. The catalytic reactions afford N-heterocycles with exceptionally high diastereo- and enantioselectivities. The [2 + 4] products are amenable for further transformations to useful molecules such as chiral piperidines and multicyclic structures. | URI: | https://hdl.handle.net/10356/97497 http://hdl.handle.net/10220/10601 |
ISSN: | 1523-7060 | DOI: | 10.1021/ol3013588 | Schools: | School of Physical and Mathematical Sciences | Rights: | © 2012 American Chemical Society. | Fulltext Permission: | none | Fulltext Availability: | No Fulltext |
Appears in Collections: | SPMS Journal Articles |
SCOPUSTM
Citations
5
77
Updated on Mar 6, 2024
Web of ScienceTM
Citations
5
72
Updated on Oct 28, 2023
Page view(s) 10
862
Updated on Mar 18, 2024
Google ScholarTM
Check
Altmetric
Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.