Please use this identifier to cite or link to this item:
https://hdl.handle.net/10356/98325
Title: | Functional mesoporous silica nanoparticles for photothermal-controlled drug delivery in vivo | Authors: | Yan, Hong Teh, Cathleen Sreejith, Sivaramapanicker Zhu, Liangliang Kwok, Anna Fang, Weiqin Ma, Xing Nguyen, Kim Truc Korzh, Vladimir Zhao, Yanli |
Keywords: | DRNTU::Engineering::Materials | Issue Date: | 2012 | Source: | Yan, H., Teh, C., Sreejith, S., Zhu, L., Kwok, A., Fang, W., et al. (2012). Functional Mesoporous Silica Nanoparticles for Photothermal-Controlled Drug Delivery In Vivo. Angewandte Chemie International Edition, 51(33), 8373-8377. | Series/Report no.: | Angewandte chemie international edition | Abstract: | Release me! A new class of photothermal-responsive [2]rotaxane-appended mesoporous silica nanoparticles (MSNPs) was developed. Remote-controlled movement of the α-cyclodextrin ring (green) upon trans–cis isomerization of the azobenzene axle (red) enables the loading and release of drugs on demand (see scheme). Curcumin-loaded MSNPs were shown to release curcumin into zebrafish larvae upon treatment with visible light or heat. | URI: | https://hdl.handle.net/10356/98325 http://hdl.handle.net/10220/12452 |
ISSN: | 1433-7851 | DOI: | 10.1002/anie.201203993 | Schools: | School of Materials Science & Engineering School of Physical and Mathematical Sciences |
Rights: | © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. | Fulltext Permission: | none | Fulltext Availability: | No Fulltext |
Appears in Collections: | SPMS Journal Articles |
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