Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/103140
Title: Phaeobacter gallaeciensis genomes from globally opposite locations reveal high similarity of adaptation to surface life
Authors: Thole, Sebastian
Kalhoefer, Daniela
Voget, Sonja
Berger, Martine
Engelhardt, Tim
Liesegang, Heiko
Wollherr, Antje
Kjelleberg, Staffan
Daniel, Rolf
Simon, Meinhard
Thomas, Torsten
Brinkhoff, Thorsten
Keywords: DRNTU::Science::Biological sciences
Issue Date: 2012
Source: Thole, S., Kalhoefer, D., Voget, S., Berger, M., Engelhardt, T., Liesegang, H., et al. (2012). Phaeobacter gallaeciensis genomes from globally opposite locations reveal high similarity of adaptation to surface life. The ISME Journal, 6, 2229-2244.
Series/Report no.: The ISME journal
Abstract: Phaeobacter gallaeciensis, a member of the abundant marine Roseobacter clade, is known to be an effective colonizer of biotic and abiotic marine surfaces. Production of the antibiotic tropodithietic acid (TDA) makes P. gallaeciensis a strong antagonist of many bacteria, including fish and mollusc pathogens. In addition to TDA, several other secondary metabolites are produced, allowing the mutualistic bacterium to also act as an opportunistic pathogen. Here we provide the manually annotated genome sequences of the P. gallaeciensis strains DSM 17395 and 2.10, isolated at the Atlantic coast of north western Spain and near Sydney, Australia, respectively. Despite their isolation sites from the two different hemispheres, the genome comparison demonstrated a surprisingly high level of synteny (only 3% nucleotide dissimilarity and 88% and 93% shared genes). Minor differences in the genomes result from horizontal gene transfer and phage infection. Comparison of the P. gallaeciensis genomes with those of other roseobacters revealed unique genomic traits, including the production of iron-scavenging siderophores. Experiments supported the predicted capacity of both strains to grow on various algal osmolytes. Transposon mutagenesis was used to expand the current knowledge on the TDA biosynthesis pathway in strain DSM 17395. This first comparative genomic analysis of finished genomes of two closely related strains belonging to one species of the Roseobacter clade revealed features that provide competitive advantages and facilitate surface attachment and interaction with eukaryotic hosts.
URI: https://hdl.handle.net/10356/103140
http://hdl.handle.net/10220/16900
DOI: 10.1038/ismej.2012.62
Schools: School of Biological Sciences 
Rights: © 2012 International Society for Microbial Ecology.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SCELSE Journal Articles

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