Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/101791
Title: Effects of moxa smoke on monoamine neurotransmitters in SAMP8 Mice
Authors: Xu, Huanfang
Zhao, Baixiao
Cui, Yingxue
Lim, Min Yee
Liu, Ping
Han, Li
Guo, Hongzhu
Lao, Lixing
Keywords: DRNTU::Science::Biological sciences
Issue Date: 2013
Source: Xu, H., Zhao, B., Cui, Y., Lim, M. Y., Liu, P., Han, L., et al. (2013). Effects of Moxa Smoke on Monoamine Neurotransmitters in SAMP8 Mice. Evidence-Based Complementary and Alternative Medicine, 2013, 178067-.
Series/Report no.: Evidence-based complementary and alternative medicine
Abstract: Objectives. To investigate the anti-aging effects of moxa smoke on SAMP8 mice. Methods. Using 2 × 3 factorial design, exposure length (15 or 30 minutes daily), and concentration (low, 5–15mg/m3; middle, 25–35mg/m3; high, 85–95mg/m3), 70 SAMP8 mice were randomly assigned, n = 10/group, to a model group or one of six moxa smoke groups: L1, L2, M1, M2, H1, or H2. Ten SAMR1 mice were used as normal control. Mice in moxa smoke groups were exposed to moxa smoke at respective concentrations and exposure lengths; the model and normal control mice were not exposed. Cerebral 5-HT, DA, and NE levels were determined using ELISA. Results. Compared to normal control, the model group showed a significant decrease in 5-HT, DA, and NE. Compared to model group, 5-HT and NE were significantly higher in groups L2,M1, andM2 andDA was significantly so in L2 andM1. 5-HT,DA, andNE levels were the highest in groupM1 amongmoxa smoke groups. Amarked exposure length × concentration interaction was observed for 5-HT, DA, and NE. Conclusion. Moxa smoke increases monoamine neurotransmitter levels, which varies according to concentration and exposure length. Our finding suggests that the middle concentration ofmoxa smoke for 15 minutes seems the most beneficial.
URI: https://hdl.handle.net/10356/101791
http://hdl.handle.net/10220/18776
ISSN: 1741-427X
DOI: 10.1155/2013/178067
Schools: School of Biological Sciences 
Rights: © 2013 The Author(s).This paper was published in Evidence-Based Complementary and Alternative Medicine and is made available as an electronic reprint (preprint) with permission of The Author(s). The paper can be found at the following official DOI: http://dx.doi.org/10.1155/2013/178067.  One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SBS Journal Articles

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