| dc.contributor.author |
Fong, Eileen. |
| dc.contributor.author |
Tirrell, David A. |
| dc.date.accessioned |
2011-07-29T01:27:42Z |
| dc.date.available |
2011-07-29T01:27:42Z |
| dc.date.copyright |
2010 |
| dc.date.issued |
2011-07-29 |
| dc.identifier.citation |
Fong, E., & Tirrell, D. A. (2010). Collective Cell Migration on Artificial Extracellular Matrix Proteins Containing Full-Length Fibronectin Domains. Advanced Materials, 22, 5271-5275. |
| dc.identifier.uri |
http://hdl.handle.net/10220/6946 |
| dc.description.abstract |
The discovery of the cell-adhesive properties of the Arg-Gly-Asp
(RGD) sequence located in the tenth type III domain of
fi bronectin triggered widespread use of RGD-functionalized
materials for directing cell behavior. [ 1,2 ] In studies of cell adhesion
and migration, however, cell responses on RGD surfaces
are never identical to those observed on fi bronectin. [ 3 ] For
example, we recently examined the attachment and patterning
of Rat-1 fi broblasts on elastin-based artifi cial extracellular matrix
(aECM) proteins bearing a fi bronectin-derived RGD sequence
and found the average projected area of such cells to be approximately
60% of those spread on fi bronectin. |
| dc.language.iso |
en |
| dc.relation.ispartofseries |
Advanced materials |
| dc.rights |
© 2010 Wiley-VCH Verlag. |
| dc.subject |
DRNTU::Engineering::Materials::Biomaterials. |
| dc.title |
Collective cell migration on artificial extracellular matrix proteins containing full-length fibronectin domains. |
| dc.type |
Journal Article |
| dc.contributor.school |
School of Materials Science and Engineering |
| dc.identifier.doi |
http://dx.doi.org/10.1002/adma.201002448 |
| dc.description.version |
Accepted version |
| dc.identifier.rims |
156327 |
