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Title:
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Labeling and tracking P2 purinergic receptors in living cells using ATP-conjugated quantum dots.
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Author:
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Jiang, Shan.; Liu, Aiping.; Duan, Hongwei.; Soo, Jianchow.; Chen, Peng.
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Copyright year:
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2011 |
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Abstract:
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It has been increasingly recognized that adenosine-5 ′ -triphosphate (ATP)
signaling through P2 purinergic receptors has a diverse infl uence on cell
functions and human health. In this contribution, a simple and non-invasive
method to specifi cally label P2 receptors using ATP-conjugated quantum dots
(QDs) is demonstrated. In addition, the endocytosis, vesicular traffi cking,
and recycling of QD-labeled P2 receptors are studied under different physiological
conditions using confocal and total internal refl ection fl uorescence
microscopy. |
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Subject:
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DRNTU::Engineering::Chemical engineering. |
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Type:
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Journal Article |
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Series/ Journal Title:
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Advanced functional materials |
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School:
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School of Chemical and Biomedical Engineering |
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Rights:
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© 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim |
