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Adhesive-based liquid metal radio-frequency microcoil for magnetic resonance relaxometry measurement

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Adhesive-based liquid metal radio-frequency microcoil for magnetic resonance relaxometry measurement

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dc.contributor.author Kong, Tian Fook
dc.contributor.author Peng, Weng Kung
dc.contributor.author Luong, Trung-Dung
dc.contributor.author Nguyen, Nam-Trung
dc.contributor.author Han, Jongyoon
dc.date.accessioned 2012-03-29T01:17:40Z
dc.date.available 2012-03-29T01:17:40Z
dc.date.copyright 2012
dc.date.issued 2012-03-29
dc.identifier.citation Kong, T. F., Peng, W. K., Luong, T. D., Nguyen. N.-T. & Han J. (2012). Adhesive-based liquid metal radio-frequency microcoil for magnetic resonance relaxometry measurement. Lab on a Chip, 12, 287-294.
dc.identifier.uri http://hdl.handle.net/10220/7690
dc.description.abstract This paper reports the fabrication and characterization of an adhesive-based liquid-metal microcoil for magnetic resonance relaxometry (MRR). Conventionally, microcoils are fabricated by various techniques such as electroplating, microcontact printing and focused ion beam milling. These techniques require considerable fabrication efforts and incur high cost. In this paper, we demonstrate a novel technique to fabricate three-dimensional multilayer liquid-metal microcoils together with the microfluidic network by lamination of dry adhesive sheets. One of the unique features of the adhesive-based technique is that the detachable sample chamber can be disposed after each experiment and the microcoil can be reused without cross-contamination multiple times. The integrated microcoil has a low direct-current (DC) resistance of 0.3 Ω and a relatively high inductance of 67.5 nH leading to a high quality factor of approximately 30 at 21.65 MHz. The microcoil was characterized for 0.5 T proton MRR measurements. The optimal pulse duration, amplitude, and frequency for the 90° pulse were 131 μs, −30 dB (1.56 W) and 21.6553 MHz, respectively. In addition, we used the liquid-metal microcoil to perform a parametric study on the transverse relaxation rate of human red blood cells at different hematocrit levels. The transverse relaxation rate increases quadratically with the hematocrit level. The results from the liquid-metal microcoil were verified by measurements with a conventional solenoid coil.
dc.format.extent 15 p.
dc.language.iso en
dc.relation.ispartofseries Lab on a chip
dc.rights © 2012 The Royal Society of Chemistry. This is the author created version of a work that has been peer reviewed and accepted for publication by Lab on a Chip, The Royal Society of Chemistry. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [DOI: http://dx.doi.org/10.1039/C1LC20853E ].
dc.subject DRNTU::Engineering::Mechanical engineering.
dc.title Adhesive-based liquid metal radio-frequency microcoil for magnetic resonance relaxometry measurement
dc.type Journal Article
dc.contributor.school School of Mechanical and Aerospace Engineering
dc.identifier.doi http://dx.doi.org/10.1039/C1LC20853E
dc.description.version Accepted version
dc.identifier.rims 163234

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