mirage

An efficient microfluidic sorter : implementation of double meandering micro striplines for magnetic particles switching

DSpace/Manakin Repository

 

Search DR-NTU


Advanced Search Subject Search

Browse

My Account

An efficient microfluidic sorter : implementation of double meandering micro striplines for magnetic particles switching

Show full item record

Title: An efficient microfluidic sorter : implementation of double meandering micro striplines for magnetic particles switching
Author: Kong, Tian Fook; E, Huan Shin; Sugiarto, Hendrik Santoso; Liew, Hwi Fen; Wang, Xinghua; Lew, Wen Siang; Nguyen, Nam-Trung; Chen, Yong
Copyright year: 2010
Abstract: The ability to trap, manipulate, and separate magnetic beads has become one of the key requirements in realizing an integrated magnetic lab-on-chip biosensing system. In this article, we present the design and fabrication of an integrated magneto-fluidic device for sorting magnetic particles with a sorting efficiency of up to 95%. The actuation and manipulation of magnetic beads are realized using microfabricated square meandering current-carrying micro striplines. The current is alternated between two neighboring micro striplines to switch the magnetic beads to either one of the two outlets. We performed a series of parametric study to investigate the effect of applied current, flow rate, and switching frequency on the sorting efficiency. Experimental results reveal that the sorting efficiency is proportional to the square of current applied to the stripline, and decreases with increasing buffer flow rate and switching frequency. Such phenomena agree well with our theoretical analysis and simulation result. The fastest switching rate, which is limited by the microchannel geometry and bead velocity, is 2 Hz.
Subject: DRNTU::Engineering::Mechanical engineering
Type: Journal Article
Series/ Journal Title: Microfluidics and nanofluidics
School: School of Mechanical and Aerospace Engineering
Rights: © 2010 Springer-Verlag. This is the author created version of a work that has been peer reviewed and accepted for publication by Microfluidics and nanofluidics, Springer-Verlag. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at:[DOI: http://dx.doi.org/10.1007/s10404-010-0735-8]

Files in this item

Files Size Format View
[Author]An effi ... ic particles switching.pdf 2.155Mb PDF View/Open
   

DOI Query

- Get published version (via Digital Object Identifier)
   

This item appears in the following Collection(s)

Show full item record

Statistics

Total views

All Items Views
An efficient microfluidic sorter : implementation of double meandering micro striplines for magnetic particles switching 239

Total downloads

All Bitstreams Views
[Author]An efficient microfluidic sorter implementation of double meandering micro striplines for magnetic particles switching.pdf 226
SortingManuscript-MicrofluidNanofluid - Revised.pdf 8

Top country downloads

Country Code Views
United States of America 106
China 16
Russian Federation 16
Singapore 15
France 10

Top city downloads

city Views
Mountain View 79
Singapore 15
Beijing 5
Henderson 4
Kiez 4