mirage

An efficient microfluidic sorter : implementation of double meandering micro striplines for magnetic particles switching

DSpace/Manakin Repository

 

Search DR-NTU


Advanced Search Subject Search

Browse

My Account

An efficient microfluidic sorter : implementation of double meandering micro striplines for magnetic particles switching

Show simple item record

dc.contributor.author Kong, Tian Fook
dc.contributor.author E, Huan Shin
dc.contributor.author Sugiarto, Hendrik Santoso
dc.contributor.author Liew, Hwi Fen
dc.contributor.author Wang, Xinghua
dc.contributor.author Lew, Wen Siang
dc.contributor.author Nguyen, Nam-Trung
dc.contributor.author Chen, Yong
dc.date.accessioned 2012-04-11T08:42:13Z
dc.date.available 2012-04-11T08:42:13Z
dc.date.copyright 2010
dc.date.issued 2012-04-11
dc.identifier.citation Kong, T. F., E, H. S., Sugiarto, H. S., Liew, H. F., Wang, X., Lew, W. S., et al. (2011). An efficient microfluidic sorter: implementation of double meandering micro striplines for magnetic particles switching. Microfluidics and Nanofluidics, 10(5), 1069-1078.
dc.identifier.uri http://hdl.handle.net/10220/7731
dc.description.abstract The ability to trap, manipulate, and separate magnetic beads has become one of the key requirements in realizing an integrated magnetic lab-on-chip biosensing system. In this article, we present the design and fabrication of an integrated magneto-fluidic device for sorting magnetic particles with a sorting efficiency of up to 95%. The actuation and manipulation of magnetic beads are realized using microfabricated square meandering current-carrying micro striplines. The current is alternated between two neighboring micro striplines to switch the magnetic beads to either one of the two outlets. We performed a series of parametric study to investigate the effect of applied current, flow rate, and switching frequency on the sorting efficiency. Experimental results reveal that the sorting efficiency is proportional to the square of current applied to the stripline, and decreases with increasing buffer flow rate and switching frequency. Such phenomena agree well with our theoretical analysis and simulation result. The fastest switching rate, which is limited by the microchannel geometry and bead velocity, is 2 Hz.
dc.format.extent 17 p.
dc.language.iso en
dc.relation.ispartofseries Microfluidics and nanofluidics
dc.rights © 2010 Springer-Verlag. This is the author created version of a work that has been peer reviewed and accepted for publication by Microfluidics and nanofluidics, Springer-Verlag. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at:[DOI: http://dx.doi.org/10.1007/s10404-010-0735-8]
dc.subject DRNTU::Engineering::Mechanical engineering
dc.title An efficient microfluidic sorter : implementation of double meandering micro striplines for magnetic particles switching
dc.type Journal Article
dc.contributor.school School of Mechanical and Aerospace Engineering
dc.identifier.doi http://dx.doi.org/10.1007/s10404-010-0735-8

Files in this item

Files Size Format View
[Author]An effi ... ic particles switching.pdf 2.155Mb PDF View/Open

This item appears in the following Collection(s)

Show simple item record

Statistics

Total views

All Items Views
An efficient microfluidic sorter : implementation of double meandering micro striplines for magnetic particles switching 217

Total downloads

All Bitstreams Views
[Author]An efficient microfluidic sorter implementation of double meandering micro striplines for magnetic particles switching.pdf 223
SortingManuscript-MicrofluidNanofluid - Revised.pdf 8

Top country downloads

Country Code Views
United States of America 106
China 16
Russian Federation 16
Singapore 15
France 10

Top city downloads

city Views
Mountain View 79
Singapore 15
Beijing 5
Henderson 4
Kiez 4