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Label-free, electrochemical detection of methicillin-resistant staphylococcus aureus DNA with reduced graphene oxide-modified electrodes

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Label-free, electrochemical detection of methicillin-resistant staphylococcus aureus DNA with reduced graphene oxide-modified electrodes

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dc.contributor.author Wang, Zhijuan
dc.contributor.author Zhang, Juan
dc.contributor.author Chen, Peng
dc.contributor.author Zhou, Xiaozhu
dc.contributor.author Yang, Yanli
dc.contributor.author Wu, Shixin
dc.contributor.author Niu, Li
dc.contributor.author Han, Yu
dc.contributor.author Wang, Lianhui
dc.contributor.author Chen, Peng
dc.contributor.author Boey, Freddy Yin Chiang
dc.contributor.author Zhang, Qichun
dc.contributor.author Bo, Liedberg
dc.contributor.author Zhang, Hua
dc.date.accessioned 2012-07-13T04:37:09Z
dc.date.available 2012-07-13T04:37:09Z
dc.date.copyright 2011
dc.date.issued 2012-07-13
dc.identifier.citation Wang, Z., Zhang, J., Chen, P., Zhou, X., Yang, Y., Wu, S., Niu, L., Han, Y., Wang, L., Chen, P., Boey, F., Zhang, Q., Liedberg, B., & Zhang, H. (2011). Label-free, Electrochemical Detection of Methicillin-Resistant Staphylococcus Aureus DNA with Reduced Graphene Oxide-Modified Electrodes. Biosensors and Bioelectronics, 26(9), 3881–3886.
dc.identifier.uri http://hdl.handle.net/10220/8333
dc.description.abstract Reduced graphene oxide (rGO)-modified glassy carbon electrode is used to detect the methicillinresistant Staphylococcus aureus (MRSA) DNA by using electrochemical impedance spectroscopy. Our experiments confirm that ssDNA, before and after hybridization with target DNA, are successfully anchored on the rGO surface. After the probe DNA, pre-adsorbed on rGO electrode, hybridizes with target DNA, the measured impedance increases dramatically. It provides a new method to detect DNA with high sensitivity (10−13 M, i.e., 100 fM) and selectivity.
dc.language.iso en
dc.relation.ispartofseries Biosensors and Bioelectronics
dc.rights © 2011 Elsevier B.V. This is the author created version of a work that has been peer reviewed and accepted for publication by Biosensors and Bioelectronics, Elsevier. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1016/j.bios.2011.03.002].
dc.subject DRNTU::Science::Medicine::Biosensors
dc.title Label-free, electrochemical detection of methicillin-resistant staphylococcus aureus DNA with reduced graphene oxide-modified electrodes
dc.type Journal Article
dc.contributor.school School of Materials Science and Engineering
dc.identifier.doi http://dx.doi.org/10.1016/j.bios.2011.03.002
dc.description.version Accepted version

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