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Double spiral detection channel for on-chip chemiluminescence detection

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Double spiral detection channel for on-chip chemiluminescence detection

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Title: Double spiral detection channel for on-chip chemiluminescence detection
Author: Lok, Khoi Seng; Kwok, Yien Chian; Nguyen, Nam-Trung
Copyright year: 2012
Abstract: In this paper, we introduced a three-layered microchip that consists of a double spiral channel design for chemiluminescence (CL) detection and a passive micromixer to facilitate the mixing of reagents. The design with two overlapping spiral channels doubled the CL intensity emitted from the reaction as compared to the design with a single spiral channel. The addition of the passive micromixer improved the signal by 1.5 times. Luminol-based chemiluminescence reaction was used for the characterization of the device. This microchip was successfully tested with the determination of L-cysteine and uric acid.
Subject: DRNTU::Engineering::Mechanical engineering.
Type: Journal Article
Series/ Journal Title: Sensors and actuators B: chemical
School: School of Mechanical and Aerospace Engineering
Rights: © 2012 Elsevier B.V. This is the author created version of a work that has been peer reviewed and accepted for publication by Sensors and Actuators B: Chemical, Elsevier B.V. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [DOI: http://dx.doi.org/10.1016/j.snb.2012.04.047].
Version: Accepted version

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