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An on-nanoparticle rolling-circle amplification platform for ultrasensitive protein detection in biological fluids.

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An on-nanoparticle rolling-circle amplification platform for ultrasensitive protein detection in biological fluids.

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Title: An on-nanoparticle rolling-circle amplification platform for ultrasensitive protein detection in biological fluids.
Author: Yan, Juan.; Song, Shiping.; Li, Bing.; Zhang, Qingzhi.; Huang, Qing.; Zhang, Hua.; Fan, Chunhai.
Copyright year: 2010
Abstract: An on-nanoparticle rolling-circle amplification (nanoRCA) strategy allows the visual detection of 30 molecules of carcinoembryonic antigen with at least 1010-fold selectivity over a range of noncognate proteins. The nanoRCA assay is applicable to the detection of two tumor markers in biological fluids: prostate-specific antigen in spiked sera and interleukin-8 in saliva.
Subject: DRNTU::Engineering::Materials.
Type: Journal Article
Series/ Journal Title: Small
School: School of Materials Science and Engineering
Rights: © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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