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Title:
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An on-nanoparticle rolling-circle amplification platform for ultrasensitive protein detection in biological fluids.
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Author:
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Yan, Juan.; Song, Shiping.; Li, Bing.; Zhang, Qingzhi.; Huang, Qing.; Zhang, Hua.; Fan, Chunhai.
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Copyright year:
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2010 |
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Abstract:
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An on-nanoparticle rolling-circle amplification (nanoRCA) strategy allows the visual detection of 30 molecules of carcinoembryonic antigen with at least 1010-fold selectivity over a range of noncognate proteins. The nanoRCA assay is applicable to the detection of two tumor markers in biological fluids: prostate-specific antigen in spiked sera and interleukin-8 in saliva. |
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Subject:
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DRNTU::Engineering::Materials. |
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Type:
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Journal Article |
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Series/ Journal Title:
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Small |
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School:
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School of Materials Science and Engineering |
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Rights:
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© 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
