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An on-nanoparticle rolling-circle amplification platform for ultrasensitive protein detection in biological fluids

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An on-nanoparticle rolling-circle amplification platform for ultrasensitive protein detection in biological fluids

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dc.contributor.author Yan, Juan
dc.contributor.author Song, Shiping
dc.contributor.author Li, Bing
dc.contributor.author Zhang, Qingzhi
dc.contributor.author Huang, Qing
dc.contributor.author Zhang, Hua
dc.contributor.author Fan, Chunhai
dc.date.accessioned 2012-09-19T08:28:43Z
dc.date.available 2012-09-19T08:28:43Z
dc.date.copyright 2010
dc.date.issued 2012-09-19
dc.identifier.citation Yan, J., Song, S., Li, B., Zhang, Q., Huang, Q., Zhang, H., et al. (2010). An on-nanoparticle rolling-circle amplification platform for ultrasensitive protein detection in biological fluids. Small, 6(22), 2520-2525.
dc.identifier.issn 1613-6829
dc.identifier.uri http://hdl.handle.net/10220/8578
dc.description.abstract An on-nanoparticle rolling-circle amplification (nanoRCA) strategy allows the visual detection of 30 molecules of carcinoembryonic antigen with at least 1010-fold selectivity over a range of noncognate proteins. The nanoRCA assay is applicable to the detection of two tumor markers in biological fluids: prostate-specific antigen in spiked sera and interleukin-8 in saliva.
dc.language.iso en
dc.relation.ispartofseries Small
dc.rights © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
dc.subject DRNTU::Engineering::Materials.
dc.title An on-nanoparticle rolling-circle amplification platform for ultrasensitive protein detection in biological fluids
dc.type Journal Article
dc.contributor.school School of Materials Science and Engineering
dc.identifier.doi http://dx.doi.org/10.1002/smll.201001220

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