Showing results 21 to 40 of 87
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| Issue Date | Title | Author(s) |
| 2023 | Cryo-electron microscopy structure of the Mycobacterium tuberculosis cytochrome bcc:aa₃ supercomplex and a novel inhibitor targeting subunit cytochrome cI | Mathiyazakan, Vikneswaran; Wong, Chui Fann; Harikishore, Amaravadhi; Pethe, Kevin; Grüber, Gerhard |
| 2023 | Cryo-EM structure of the Mycobacterium abscessus F1-ATPase | Wong, Chui Fann; Leow, Chen Yen; Grüber, Gerhard |
| 2014 | Crystal structure of subunits D and F in complex gives insight into energy transmission of the eukaryotic V-ATPase from Saccharomyces cerevisiae | Balakrishna, Asha Manikkoth; Basak, Sandip; Manimekalai, Malathy Sony Subramanian; Grüber, Gerhard |
| 2012 | Crystallization and preliminary X-ray crystallographic analysis of subunit F (F1-94), an essential coupling subunit of the eukaryotic V1VO-ATPase from Saccharomyces cerevisiae | Basak, Sandip; Balakrishna, Asha Manikkoth; Manimekalai, Malathy Sony Subramanian; Grüber, Gerhard |
| 2018 | Crystallographic and enzymatic insights into the mechanisms of Mg-ADP inhibition in the A1 complex of the A1AO ATP synthase | Singh, Dhirendra; Grüber, Gerhard |
| 2014 | Crystallographic structure of the turbine C-ring from spinach chloroplast F-ATP synthase | Seelert, Holger; Marx, Sven‑Hendric; Dencher, Norbert A.; Grüber, Gerhard; Balakrishna, Asha Manikkoth |
| 2016 | Deletion of a unique loop in the mycobacterial F-ATP synthase γ subunit sheds light on its inhibitory role in ATP hydrolysis-driven H+ pumping | Hotra, Adam; Suter, Manuel; Biuković, Goran; Priya, Ragunathan; Kundu, Subhashri; Dick, Thomas; Grüber, Gerhard |
| 2020 | Discovery of a novel mycobacterial F-ATP synthase inhibitor and its potency in combination with diarylquinolines | Hotra, Adam; Ragunathan, Priya; Ng, Pearly Shuyi; Seankongsuk, Pattarakiat; Harikishore, Amaravadhi; Sarathy, Jickky Palmae; Saw, Wuan-Geok; Lakshmanan, Umayal; Sae-Lao, Patcharaporn; Kalia, Nitin Pal; Shin, Joon; Kalyanasundaram, Revathy; Anbarasu, Sivaraj; Parthasarathy, Krupakar; Pradeep, Chaudhari Namrata; Makhija, Harshyaa; Dröge, Peter; Poulsen, Anders; Tan, Jocelyn Hui Ling; Pethe, Kevin; Dick, Thomas; Bates, Roderick Wayland; Grüber, Gerhard |
| 2019 | Disrupting coupling within mycobacterial F-ATP synthases subunit ε causes dysregulated energy production and cell wall biosynthesis | Saw, Wuan-Geok; Wu, Mu-Lu; Ragunathan, Priya; Biuković, Goran; Lau, Aik-Meng; Shin, Joon; Harikishore, Amaravadhi; Cheung, Chen-Yi; Hards, Kiel; Sarathy, Jickky Palmae; Bates, Roderick Wayland; Cook, Gregory M.; Dick, Thomas; Grüber, Gerhard |
| 2013 | The DNA uptake ATPase PilF of Thermus thermophilus : a reexamination of the zinc content | Nies, Dietrich H.; Salzer, Ralf; Herzberg, Martin; Biuković, Goran; Grüber, Gerhard; Müller, Volker; Averhoff, Beate |
| 2021 | Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosis | Lee, Bei Shi; Hards, Kiel; Engelhart, Curtis A.; Hasenoehrl, Erik J.; Kalia, Nitin Pal; Mackenzie, Jared S.; Sviriaeva, Ekaterina; Chong, Sherilyn Shi Min; Manimekalai, Malathy Sony S.; Koh, Vanessa H.; Chan, John; Xu, Jiayong; Alonso, Sylvie; Miller, Marvin J.; Steyn, Adrie J. C.; Grüber, Gerhard; Schnappinger, Dirk; Berney, Michael; Cook, Gregory M.; Moraski, Garrett C.; Pethe, Kevin |
| 2013 | Effect of Ser392 Phosphorylation on the Structure and Dynamics of the Polybasic Domain of ADP Ribosylation Factor Nucleotide Site Opener Protein: A Molecular Simulation Study | Srinivasaraghavan, Kannan; Nacro, Kassoum; Grüber, Gerhard; Verma, Chandra Shekhar |
| 2019 | Effect of the additional cysteine 503 of vancomycin-resistant Enterococcus faecalis (V583) alkylhydroperoxide reductase subunit F (AhpF) and the mechanism of AhpF and subunit C assembling | Toh, Yew Kwang; Shin, Joon; Balakrishna, Asha Manikkoth; Kamariah, Neelagandan; Grüber, Ardina; Eisenhaber, Frank; Eisenhaber, Birgit; Grüber, Gerhard |
| 2017 | Essential role of the flexible linker on the conformational equilibrium of bacterial peroxiredoxin reductase for effective regeneration of peroxiredoxin | Grüber, Gerhard; Kamariah, Neelagandan; Eisenhaber, Birgit; Eisenhaber, Frank |
| 2017 | Exploiting the synthetic lethality between terminal respiratory oxidases to kill
Mycobacterium tuberculosis
and clear host infection | Hasenoehrl, Erik J.; Koh, Vanessa H.; Ang, Michelle L. T.; Sajorda, Dannah R.; Hards, Kiel; Grüber, Gerhard; Alonso, Sylvie; Cook, Gregory M.; Berney, Michael; Pethe, Kevin; Kalia, Nitin Pal; Ab Rahman, Nurlilah Binte |
| 2023 | The FGFR inhibitor PD173074 binds to the C-terminus of oncofetal HMGA2 and modulates its DNA-binding and transcriptional activation functions | Ahmed, Syed Moiz; Ragunathan, Priya; Shin, Joon; Peter, Sabrina; Kleissle, Sabrina; Neuenschwander, Martin; Schäfer, Reinhold; Kries, Jens Peter V.; Grüber, Gerhard; Dröge, Peter |
| 2023 | GaMF1.39’s antibiotic efficacy and its enhanced antitubercular activity in combination with Clofazimine, Telacebec, ND-011992 or TBAJ-876 | Ragunathan, Priya; Ng, Pearly Shuyi; Singh, Samsher; Poh, Wee Han; Litty, Dennis; Kalia, Nitin Pal; Larsson, Simon; Harikishore, Amaravadhi; Rice, Scott A.; Ingham, Philip William; Müller, Volker; Moraski, Garrett; Miller, Marvin J.; Dick, Thomas; Pethe, Kevin; Grüber, Gerhard |
| 2018 | Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from
Pseudomonas aeruginosa | Liu, Chong; Liew, Chong Wai; Wong, Yee Hwa; Tan, Siok Thing; Poh, Wee Han; Manimekalai, Malathy S. S.; Rajan, Sreekanth; Xin, Lingyi; Liang, Zhao-Xun; Grüber, Gerhard; Rice, Scott A.; Lescar, Julien |
| 2020 | Introduction : novel insights into TB research and drug discovery | Grüber, Gerhard |
| 2012 | Low resolution solution structure of HAMLET and the importance of its alpha-domains in tumoricidal activity | Ho, James C. S.; Rydstrom, Anna; Manimekalai, Malathy Sony Subramanian; Svanborg, Catharina; Grüber, Gerhard |