Showing results 1 to 20 of 28
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| Issue Date | Title | Author(s) |
| 2015 | Assessing the Efficacy of Mdm2/Mdm4-Inhibiting Stapled Peptides Using Cellular Thermal Shift Assays | Brown, Christopher J.; Ferrer, Fernando J.; Yuen, Tsz Ying; Quah, Soo Tng; Chan, Boon Hong; Teo, Hsiang Ling; Nordlund, Pär; Lane, David P.; Tan, Ban Xiong; Jansson, Anna Elisabet |
| 2015 | Biochemical and biophysical characterization of human 15LOX-2 and protein : protein interactions study of sphingosine kinase 1 | Yeung, Kit |
| 2015 | The cellular thermal shift assay : a novel biophysical assay for in situ drug target engagement and mechanistic biomarker studies | Martinez Molina, Daniel; Nordlund, Pär |
| 2020 | Cellular thermal shift assay for the identification of drug-target interactions in the Plasmodium falciparum proteome | Dziekan, Jerzy Michal; Wirjanata, Grennady; Dai, Lingyun; Go, Ka Diam; Yu, Han; Lim, Yan Ting; Chen, Liyan; Wang, Loo Chien; Puspita, Brenda; Prabhu, Nayana; Sobota, Radoslaw M.; Nordlund, Pär; Bozdech, Zbynek |
| 2016 | CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil | Almqvist, Helena; Axelsson, Hanna; Jafari, Rozbeh; Dan, Chen; Mateus, André; Haraldsson, Martin; Larsson, Andreas; Molina, Daniel Martinez; Artursson, Per; Lundbäck, Thomas; Nordlund, Pär |
| 2019 | CETSA-based target engagement of taxanes as biomarkers for efficacy and resistance | Langebäck, Anette; Bacanu, Smaranda; Laursen, Henriette; Mout, Lisanne; Seki, Takahiro; Erkens-Schulze, Sigrun; Ramos, Anderson Daniel; Berggren, Anna; Cao, Yihai; Hartman, Johan; van Weerden, Wytske; Bergh, Jonas; Nordlund, Pär; Lööf, Sara |
| 2013 | The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor | Hew, Kelly; Dahlroth, Sue-Li; Venkatachalam, Rajakannan; Nasertorabi, Fariborz; Lim, Bee Ting; Cornvik, Tobias Carl; Nordlund, Pär |
| 2017 | Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality | Dai, Lingyun; Prabhu, Nayana; Diam, Go Ka; Sobota, Radoslaw; Larsson, Andreas; Nordlund, Pär; McCormick, Frank; Ghosh, Sujoy; Epstein, David M.; Dymock, Brian W.; Lee, Sang Hyun; Kitagawa, Mayumi; Liao, Pei-Ju; Lee, Kyung Hee; Wong, Jasmine; Shang, See Cheng; Minami, Noriaki; Sampetrean, Oltea; Saya, Hideyuki |
| 2018 | An efficient proteome-wide strategy for discovery and characterization of cellular nucleotide-protein interactions | Lim, Yan Ting; Prabhu, Nayana; Dai, Lingyun; Go, Ka Diam; Chen, Dan; Sreekumar, Lekshmy; Egeblad, Louise; Eriksson, Staffan; Chen, Liyan; Veerappan, Saranya; Teo, Hsiang Ling; Tan, Chris Soon Heng; Lengqvist, Johan; Larsson, Andreas; Sobota, Radoslaw M.; Nordlund, Pär |
| 2013 | Engineering protein thermostability using a generic activity-independent biophysical screen inside the cell | Asial, Ignacio; Cheng, Yue Xiang; Engman, Henrik; Dollhopf, Maria; Wu, Binghuang; Nordlund, Pär; Cornvik, Tobias |
| 2012 | High-resolution insights into binding of unfolded polypeptides by the PPIase chaperone SlpA | Löw, Christian; Nordlund, Pär; Quistgaard, Esben M. |
| 2019 | Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay | Dziekan, Jerzy Michal; Yu, Han; Chen, Dan; Dai, Lingyun; Wirjanata, Grennady; Larsson, Andreas; Prabhu, Nayana; Sobota, Radoslaw Mikolaj; Bozdech, Zbynek; Nordlund, Pär |
| 2018 | Modulation of protein-interaction states through the cell cycle | Dai, Lingyun; Zhao, Tianyun; Bisteau, Xavier; Sun, Wendi; Prabhu, Nayana; Lim, Yan Ting; Sobota, Radoslaw M.; Kaldis, Philipp; Nordlund, Pär |
| 2016 | Molecular insights into substrate recognition and catalytic mechanism of the chaperone and FKBP peptidyl-prolyl isomerase SlyD | Quistgaard, Esben M.; Weininger, Ulrich; Ural-Blimke, Yonca; Modig, Kristofer; Nordlund, Pär; Akke, Mikael; Löw, Christian |
| 2019 | Monitoring structural modulation of redox-sensitive proteins in cells with MS-CETSA | Sun, Wendi; Dai, Lingyun; Yu, Han; Puspita, Brenda; Zhao, Tianyun; Li, Feng; Tan, Justin L.; Lim, Yan Ting; Chen, Ming Wei; Sobota, Radoslaw M.; Tenen, Daniel G.; Prabhu, Nayana; Nordlund, Pär |
| 2013 | Nanobody mediated crystallization of an archeal mechanosensitive channel | Moberg, Per; Quistgaard, Esben M.; Löw, Christian; Yau, Yin Hoe; Pardon, Els; Jegerschöld, Caroline; Wåhlin, Lisa; Geifman-Shochat, Susana; Steyaert, Jan; Nordlund, Pär |
| 2012 | Optimisation of over-expression in E. coli and biophysical characterisation of human membrane protein synaptogyrin 1 | Löw, Christian; Jegerschöld, Caroline; Kovermann, Michael; Moberg, Per; Nordlund, Pär |
| 2012 | Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism | Egeblad, Louise; Welin, Martin; Flodin, Susanne; Gräslund, Susanne; Wang, Liya; Balzarini, Jan; Eriksson, Staffan; Nordlund, Pär |
| 2017 | Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states | Chen, Dan; Jansson, Anna; Sim, Daniel; Larsson, Andreas; Nordlund, Pär |
| 2014 | Structural and biochemical characterization of Human PR70 in isolation and in complex with the scaffolding subunit of protein phosphatase 2A | Dovega, Rebecca; Tsutakawa, Susan; Quistgaard, Esben M.; Anandapadamanaban, Madhanagopal; Löw, Christian; Nordlund, Pär |