Browsing by Author Kannan, Srinivasaraghavan
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| Issue Date | Title | Author(s) | |
|---|---|---|---|
 | 2021 | A chemical biology approach reveals a dependency of glioblastoma on biotin distribution | Yoon, Jeehyun; Grinchuk, Oleg V.; Kannan, Srinivasaraghavan; Ang, Melgious Jin Yan; Li, Zhenglin; Tay, Emmy Xue Yun; Lok, Ker Zhing; Lee, Bernice Woon Li; Chuah, You Heng; Chia, Kimberly; Tirado-Magallanes, Roberto; Liu, Chenfei; Zhao, Haonan; Hor, Jin Hui; Lim, Jhin Jieh; Benoukraf, Touati; Toh, Tan Boon; Chow, Edward Kai-Hua; Kovalik, Jean-Paul; Ching, Jianhong; Ng, Shi-Yan; Koh, Ming Joo; Liu, Xiaogang; Verma, Chandra Shekhar; Ong, Derrick Sek Tong |
| 2021 | Computational design of macrocyclic binders of S100B(ββ): novel peptide theranostics | Kannan, Srinivasaraghavan; Aronica, Pietro G. A.; Nguyen, Thanh Binh; Li, Jianguo; Verma, Chandra Shekhar |
| 2018 | Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket | Kannan, Srinivasaraghavan; Venkatachalam, Gireedhar; Lim, Hong Hwa; Surana, Uttam; Verma, Chandra |
| 2020 | Critical role for cold shock protein YB-1 in cytokinesis | Mehta, Sunali; Algie, Michael; Al-Jabry, Tariq; McKinney, Cushla; Kannan, Srinivasaraghavan; Verma, Chandra Shekhar; Ma, Weini; Zhang, Jessie; Bartolec, Tara K.; Masamsetti, V. Pragathi; Parker, Kim; Henderson, Luke; Gould, Maree L.; Bhatia, Puja; Harfoot, Rhodri; Chircop, Megan; Kleffmann, Torsten; Cohen, Scott B.; Woolley, Adele G.; Cesare, Anthony J.; Braithwaite, Antony |
| 2020 | Dephosphorylation of YB-1 is required for nuclear localisation during G2 phase of the cell cycle | Mehta, Sunali; McKinney, Cushla; Algie, Michael; Verma, Chandra Shekhar; Kannan, Srinivasaraghavan; Harfoot, Rhodri; Bartolec, Tara K.; Bhatia, Puja; Fisher, Alistair J.; Gould, Maree L.; Parker, Kim; Cesare, Anthony J.; Cunliffe, Heather E.; Cohen, Scott B.; Kleffmann, Torsten; Braithwaite, Antony W.; Woolley, Adele G. |
| 2019 | The dual interactions of p53 with MDM2 and p300 : implications for the design of MDM2 inhibitors | Kannan, Srinivasaraghavan; Partridge, Anthony William; Lane, David P.; Verma, Chandra Shekhar |
| 2018 | Effects of single nucleotide polymorphisms on the binding of afatinib to EGFR : a potential patient stratification factor revealed by modeling studies | Kannan, Srinivasaraghavan; Tan, Daniel Shao-Weng; Verma, Chandra Shekhar |
| 2017 | Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib | Kannan, Srinivasaraghavan; Pradhan, Mohan R.; Tiwari, Garima; Tan, Wei-Chong; Chowbay, Balram; Tan, Eng Huat; Tan, Daniel Shao-Weng; Verma, Chandra |
| 2019 | Inhibiting S100B(ββ) for activating wild-type p53 : design of stapled peptides | Kannan, Srinivasaraghavan; Aronica, Pietro G. A.; Tan, Yaw Sing; Verma, Chandra Shekhar |
| 2019 | An inter-subunit protein-peptide interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone Reptin | Coufalova, Dominika; Remnant, Lucy; Hernychova, Lenka; Muller, Petr; Healy, Alan; Kannan, Srinivasaraghavan; Westwood, Nicholas; Verma, Chandra Shekhar; Vojtesek, Borek; Hupp, Ted R.; Houston, Douglas R. |
| 2016 | Long range recognition and selection in IDPs : the interactions of the C-terminus of p53 | Kannan, Srinivasaraghavan; Lane, David P.; Verma, Chandra Shekhar |
| 2014 | mAb806 binding to epidermal growth factor receptor: a computational study | Ng, Yao Zong; Kannan, Srinivasaraghavan; Lane, David P.; Fuentes, Gloria; Verma, Chandra Shekhar | |
| 2022 | Molecular descriptors suggest stapling as a strategy for optimizing membrane permeability of cyclic peptides | Li, Jianguo; Kannan, Srinivasaraghavan; Aronica, Pietro; Brown, Christopher J.; Partridge, Anthony W.; Verma, Chandra Shekhar |
| 2015 | Mussel adhesion is dictated by time-regulated secretion and molecular conformation of mussel adhesive proteins | Petrone, Luigi; Kumar, Akshita; Sutanto, Clarinda N.; Patil, Navinkumar J.; Kannan, Srinivasaraghavan; Palaniappan, Alagappan; Amini, Shahrouz; Zappone, Bruno; Verma, Chandra; Miserez, Ali |
| 2018 | Optimization of selective mitogen-activated protein kinase interacting kinases 1 and 2 inhibitors for the treatment of blast crisis leukemia | Yang, Haiyan; Chennamaneni, Lohitha Rao; Ho, Melvyn Wai Tuck; Ang, Shi Hua; Tan, Eldwin Sum Wai; Jeyaraj, Duraiswamy Athisayamani; Yeap, Yoon Sheng; Liu, Boping; Ong, Esther H. Q.; Joy, Joma Kanikadu; Wee, John Liang Kuan; Kwek, Perlyn; Retna, Priya; Dinie, Nurul; Nguyen, Thuy Thi Hanh; Tai, Shi Jing; Manoharan, Vithya; Pendharkar, Vishal; Low, Choon Bing; Chew, Yun Shan; Vuddagiri, Susmitha; Sangthongpitag, Kanda; Choong, Meng Ling; Lee, May Ann; Kannan, Srinivasaraghavan; Verma, Chandra Shekhar; Poulsen, Anders; Lim, Sharon; Chuah, Charles Thuan Heng; Ong, Tiong Sin; Hill, Jeffrey; Matter, Alex; Nacro, Kassoum | |
| 2021 | The polybasic insert, the RBD of the SARS-CoV-2 spike protein, and the feline coronavirus - evolved or yet to evolve | Budhraja, Anshul; Pandey, Sakshi; Kannan, Srinivasaraghavan; Verma, Chandra Shekhar; Venkatraman, Prasanna |
| 2019 | Preclinical characteristics of the irreversible pan-HER kinase inhibitor neratinib compared with lapatinib : implications for the treatment of HER2-positive and HER2-mutated breast cancer | Collins, Denis M.; Conlon, Neil T.; Kannan, Srinivasaraghavan; Verma, Chandra Shekhar; Eli, Lisa D.; Lalani, Alshad S.; Crown, John |
| 2015 | Probing the Binding Mechanism of Mnk Inhibitors by Docking and Molecular Dynamics Simulations | Kannan, Srinivasaraghavan; Poulsen, Anders; Yang, Hai Yan; Ho, Melvyn; Ang, Shi Hua; Eldwin, Tan Sum Wai; Jeyaraj, Duraiswamy Athisayamani; Chennamaneni, Lohitha Rao; Liu, Boping; Hill, Jeffrey; Verma, Chandra Shekhar; Nacro, Kassoum | |
| 2019 | Simulations of mutant p53 DNA binding domains reveal a novel druggable pocket | Siau, Jia Wei; Kannan, Srinivasaraghavan; Ouaray, Zohra; Kwoh, Chee Keong; Ghadessy, Farid; Pradhan, Mohan Rajan; Nguyen, Minh N.; Lane, David P.; Verma, Chandra Shekhar |
| 2017 | Small molecules targeting the inactive form of the Mnk1/2 kinases | Kannan, Srinivasaraghavan; Pradhan, Mohan R.; Cherian, Joseph; Joseph, Thomas L.; Poh, Zhi Ying; Hai Yan, Yang; Melvyn, Ho; Boping, Liu; Jeffrey, Hill; Nacro, Kassoum; Verma, Chandra Shekhar |