Browsing by Author Lescar, Julien


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Issue DateTitleAuthor(s)
2017Allosteric pyruvate kinase-based “logic gate” synergistically senses energy and sugar levels in Mycobacterium tuberculosisZhong, Wenhe; Cui, Liang; Goh, Boon Chong; Cai, Qixu; Ho, Peiying; Chionh, Yok Hian; Yuan, Meng; Sahili, Abbas El; Fothergill-Gilmore, Linda A.; Walkinshaw, Malcolm D.; Lescar, Julien; Dedon, Peter Christian
2008Antibodies targeting the PfRH1 binding domain inhibit invasion of plasmodium falciparum merozoitesIyer, Jayasree K.; Genesan, Saraswathy; Rajamanonmani, Ravikumar; Lescar, Julien; Bozdech, Zbynek; Preiser, Peter Rainer; Gao, Xiaohong; Yeo, Kim Pin; Aw, Sharon Siqi; Kuss, Claudia
 2014Biomimetic production of silk-like recombinant squid sucker ring teeth proteinsDing, Dawei; Guerette, Paul A.; Hoon, Shawn; Kong, Kiat Whye; Cornvik, Tobias; Nilsson, Martina; Kumar, Akshita; Lescar, Julien; Miserez, Ali
 2014Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptidesChoo, Joanna A. L.; Thong, Sock Yue; Yap, Jiawei; van Esch, Wim J. E.; Raida, Manfred; Meijers, Rob; Lescar, Julien; Verhelst, Steven H. L.; Grotenbreg, Gijsbert M.
2016The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus ProductionChan, Kitti W. K.; Tay, Moon Y. F.; Smith, Kate; Ng, Ivan H. W.; Zhao, Yongqian; Ooi, Eng Eong; Lescar, Julien; Luo, Dahai; Jans, David A.; Forwood, Jade K.; Vasudevan, Subhash G.
2014The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replicationTay, Moon Y. F.; Saw, Wuan Geok; Zhao, Yongqian; Chan, Kitti W. K.; Singh, Daljit; Chong, Yuwen; Forwood, Jade K.; Ooi, Eng Eong; Grüber, Gerhard; Lescar, Julien; Luo, Dahai; Vasudevan, Subhash G.
2017Chikungunya virus nsP4 RNA-dependent RNA polymerase core domain displays detergent-sensitive primer extension and terminal adenylyltransferase activitiesChen, Ming Wei; Tan, Yaw Bia; Zheng, Jie; Zhao, Yongqian; Lim, Bee Ting; Cornvik, Tobias; Lescar, Julien; Ng, Lisa Fong Poh; Luo, Dahai
2013Conformational flexibility of the dengue virus RNA-dependent RNA polymerase revealed by a complex with an inhibitorYap, Lijian; Lescar, Julien; Noble, Christian G.; Lim, Siew Pheng; Chen, Yen-Liang; Liew, Chong Wai; Shi, Pei-Yong
 2012Crystal structure of the acyltransferase domain of the iterative polyketide synthase in enediyne biosynthesisLiew, Chong Wai; Nilsson, Martina; Chen, Ming Wei; Sun, Huihua; Cornvik, Tobias Carl; Liang, Zhao-Xun; Lescar, Julien
2015A crystal structure of the dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replicationZhao, Yongqian; Soh, Tingjin Sherryl; Zheng, Jie; Chan, Kitti Wing Ki; Phoo, Wint Wint; Lee, Chin Chin; Tay, Moon Y. F.; Swaminathan, Kunchithapadam; Cornvik, Tobias Carl; Lim, Siew Pheng; Shi, Pei-Yong; Lescar, Julien; Vasudevan, Subhash G.; Luo, Dahai
 2008Crystal structure of the FK506 binding domain of plasmodium falciparum FKBP35 in complex with FK506Kotaka, Masayo; Ye, Hong; Alag, Reema; Hu, Guangan; Bozdech, Zbynek; Preiser, Peter Rainer; Yoon, Ho Sup; Lescar, Julien
2014Crystallization and preliminary crystallographic analysis of human aquaporin 1 at a resolution of 3.28 ÅTorres, Jaume; Ruiz Carrillo, David; To Yiu Ying, Janet; Darwis, Dina; Soon, Cin Huang; Cornvik, Tobias; Lescar, Julien
2015Crystallization and X-ray diffraction analysis of the HMG domain of the chondrogenesis master regulator Sox9 in complex with a ChIP-Seq-identified DNA elementVivekanandan, Saravanan; Moovarkumudalvan, Balasubramanian; Lescar, Julien; Kolatkar, Prasanna R.
2019Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01Gu, Yue; Wong, Yee Hwa; Liew, Chong Wai; Chan, Conrad E. Z.; Murali, Tanusya M.; Yap, Jiawei; Too, Chien Tei; Purushotorman, Kiren; Hamidinia, Maryam; El Sahili, Abbas; Goh, Angeline T. H.; Teo, Rachel Z. C.; Wood, Kathryn J.; Hanson, Brendon J.; Gascoigne, Nicholas R. J.; Lescar, Julien; Vathsala, Anantharaman; MacAry, Paul A.
2017Dengue Virus Non-Structural Protein 5El Sahili, Abbas; Lescar, Julien
2014Dimerization of flavivirus NS4B proteinDong, Hongping; Reynaud, Aline; Zou, Jing; Xie, Xuping; Lee, Le Tian; Chandrasekaran, Ramya; Yap, Lijian; Wang, Qing-Yin; Kang, Congbao; Yuan, Zhiming; Lescar, Julien; Shi, Pei-Yong
2015Discovery of Dengue Virus NS4B InhibitorsWang, Qing-Yin; Dong, Hongping; Zou, Bin; Karuna, Ratna; Wan, Kah Fei; Zou, Jing; Susila, Agatha; Yip, Andy; Shan, Chao; Yeo, Kim Long; Xu, Haoying; Ding, Mei; Chan, Wai Ling; Gu, Feng; Seah, Peck Gee; Liu, Wei; Lakshminarayana, Suresh B.; Kang, CongBao; Lescar, Julien; Blasco, Francesca; Smith, Paul W.; Shi, Pei-Yong
2014Expression, purification, crystallization and preliminary X-ray analysis of full-length human RIG-IKwok, Jane; Hui, Kenrie P. Y.; Lescar, Julien; Kotaka, Masayo
2012Expression, purification, crystallization and preliminary X-ray analysis of Plasmodium falciparum GTP:AMP phosphotransferaseLaw, Alan W. L.; Hao, Quan; Kotaka, Masayo; Lescar, Julien
2015The flavivirus NS2B–NS3 protease–helicase as a target for antiviral drug developmentLuo, Dahai; Vasudevan, Subhash; Lescar, Julien