Browsing by Author Luo, Dahai

Showing results 1 to 18 of 18
Issue DateTitleAuthor(s)
2016The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus ProductionChan, Kitti W. K.; Tay, Moon Y. F.; Smith, Kate; Ng, Ivan H. W.; Zhao, Yongqian; Ooi, Eng Eong; Lescar, Julien; Luo, Dahai; Jans, David A.; Forwood, Jade K.; Vasudevan, Subhash G.
2014The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replicationTay, Moon Y. F.; Saw, Wuan Geok; Zhao, Yongqian; Chan, Kitti W. K.; Singh, Daljit; Chong, Yuwen; Forwood, Jade K.; Ooi, Eng Eong; Grüber, Gerhard; Lescar, Julien; Luo, Dahai; Vasudevan, Subhash G.
2017Chikungunya virus nsP4 RNA-dependent RNA polymerase core domain displays detergent-sensitive primer extension and terminal adenylyltransferase activitiesChen, Ming Wei; Tan, Yaw Bia; Zheng, Jie; Zhao, Yongqian; Lim, Bee Ting; Cornvik, Tobias; Lescar, Julien; Ng, Lisa Fong Poh; Luo, Dahai
2015A crystal structure of the dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replicationZhao, Yongqian; Soh, Tingjin Sherryl; Zheng, Jie; Chan, Kitti Wing Ki; Phoo, Wint Wint; Lee, Chin Chin; Tay, Moon Y. F.; Swaminathan, Kunchithapadam; Cornvik, Tobias Carl; Lim, Siew Pheng; Shi, Pei-Yong; Lescar, Julien; Vasudevan, Subhash G.; Luo, Dahai
2016Crystal structure of unlinked NS2B-NS3 protease from Zika virusZhang, Zhenzhen; Li, Yan; Loh, Ying Ru; Phoo, Wint Wint; Hung, Alvin W.; Kang, CongBao; Luo, Dahai
2015The flavivirus NS2B–NS3 protease–helicase as a target for antiviral drug developmentLuo, Dahai; Vasudevan, Subhash; Lescar, Julien
2015Flexibility of NS5 Methyltransferase-Polymerase Linker Region Is Essential for Dengue Virus ReplicationZhao, Yongqian; Soh, Tingjin Sherryl; Chan, Kitti Wing Ki; Fung, Sarah Suet Yin; Swaminathan, Kunchithapadam; Lim, Siew Pheng; Shi, Pei-Yong; Huber, Thomas; Lescar, Julien; Luo, Dahai; Vasudevan, Subhash G.
2014Functional interplay among the flavivirus NS3 protease, helicase, and cofactorsLi, Kuohan; Phoo, Wint Wint; Luo, Dahai
2014High-resolution HDX-MS reveals distinct mechanisms of RNA recognition and activation by RIG-I and MDA5Liu, Chuan-Fa; Zheng, Jie; Yong, Hui Yee; Panutdaporn, Nantika; Tang, Kai; Luo, Dahai
2018Luteolin escape mutants of dengue virus map to prM and NS2B and reveal viral plasticity during maturationVasudevan, Subhash G.; Peng, Minhua; Swarbrick, Crystall Marie Dawn; Chan, Kitti Wing-Ki; Luo, Dahai; Zhang, Wei; Lai, Xiaoping; Li, Geng
2017Luteolin restricts dengue virus replication through inhibition of the proprotein convertase furinPeng, Minhua; Watanabe, Satoru; Chan, Kitti Wing Ki; He, Qiuyan; Zhao, Ya; Zhang, Zhongde; Lai, Xiaoping; Luo, Dahai; Vasudevan, Subhash G.; Li, Geng
2015Molecular basis for specific viral RNA recognition and 2' -O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)Zhao, Yongqian; Soh, Tingjin Sherryl; Lim, Siew Pheng; Chung, Ka Yan; Swaminathan, Kunchithapadam; Vasudevan, Subhash G.; Shi, Pei-Yong; Lescar, Julien; Luo, Dahai
2017NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replicationSwarbrick, Crystall M. D.; Basavannacharya, Chandrakala; Chan, Kitti W. K.; Chan, Shu-Ann; Singh, Daljit; Wei, Na; Phoo, Wint Wint; Luo, Dahai; Lescar, Julien; Vasudevan, Subhash G.
2019RIG-I activation by a designer short RNA ligand protects human immune cells against dengue virus infection without causing cytotoxicityFink, Katja; Ho, Victor; Yong, Hui Yee; Chevrier, Marion; Narang, Vipin; Lum, Josephine; Toh, Ying-Xiu; Lee, Bernett; Chen, Jinmiao; Tan, Ern Yu; Luo, Dahai
2014The RIG-I ATPase core has evolved a functional requirement for allosteric stabilization by the Pincer domainRawling, David C.; Kohlway, Andrew S.; Luo, Dahai; Ding, Steve C.; Pyle, Anna Marie
2016Structure of the NS2B-NS3 protease from Zika virus after self-cleavagePhoo, Wint Wint; Li, Yan; Zhang, Zhenzhen; Lee, Michelle Yueqi; Loh, Ying Ru; Tan, Yaw Bia; Ng, Elizabeth Yihui; Lescar, Julien; Kang, CongBao; Luo, Dahai
2018Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitorsPhoo, Wint Wint; Zhang, Zhenzhen; Wirawan, Melissa; Chew, Edwin Jun Chen; Chew, Alvin Bing Liang; Kouretova, Jenny; Steinmetzer, Torsten; Luo, Dahai
2014Toward a crystal-clear view of the viral RNA sensing and response by RIG-I-like receptorsLuo, Dahai