Browsing by Author Nordlund, Pär

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Issue DateTitleAuthor(s)
2015Assessing the Efficacy of Mdm2/Mdm4-Inhibiting Stapled Peptides Using Cellular Thermal Shift AssaysBrown, Christopher J.; Ferrer, Fernando J.; Yuen, Tsz Ying; Quah, Soo Tng; Chan, Boon Hong; Teo, Hsiang Ling; Nordlund, Pär; Lane, David P.; Tan, Ban Xiong; Jansson, Anna Elisabet
2015Biochemical and biophysical characterization of human 15LOX-2 and protein : protein interactions study of sphingosine kinase 1Yeung, Kit
 2015The cellular thermal shift assay : a novel biophysical assay for in situ drug target engagement and mechanistic biomarker studiesMartinez Molina, Daniel; Nordlund, Pär
2016CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracilAlmqvist, Helena; Axelsson, Hanna; Jafari, Rozbeh; Dan, Chen; Mateus, André; Haraldsson, Martin; Larsson, Andreas; Molina, Daniel Martinez; Artursson, Per; Lundbäck, Thomas; Nordlund, Pär
2013The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factorHew, Kelly; Dahlroth, Sue-Li; Venkatachalam, Rajakannan; Nasertorabi, Fariborz; Lim, Bee Ting; Cornvik, Tobias Carl; Nordlund, Pär
2017Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethalityDai, Lingyun; Prabhu, Nayana; Diam, Go Ka; Sobota, Radoslaw; Larsson, Andreas; Nordlund, Pär; McCormick, Frank; Ghosh, Sujoy; Epstein, David M.; Dymock, Brian W.; Lee, Sang Hyun; Kitagawa, Mayumi; Liao, Pei-Ju; Lee, Kyung Hee; Wong, Jasmine; Shang, See Cheng; Minami, Noriaki; Sampetrean, Oltea; Saya, Hideyuki
2018An efficient proteome-wide strategy for discovery and characterization of cellular nucleotide-protein interactionsLim, Yan Ting; Prabhu, Nayana; Dai, Lingyun; Go, Ka Diam; Chen, Dan; Sreekumar, Lekshmy; Egeblad, Louise; Eriksson, Staffan; Chen, Liyan; Veerappan, Saranya; Teo, Hsiang Ling; Tan, Chris Soon Heng; Lengqvist, Johan; Larsson, Andreas; Sobota, Radoslaw M.; Nordlund, Pär
 2013Engineering protein thermostability using a generic activity-independent biophysical screen inside the cellAsial, Ignacio; Cheng, Yue Xiang; Engman, Henrik; Dollhopf, Maria; Wu, Binghuang; Nordlund, Pär; Cornvik, Tobias
 2012High-resolution insights into binding of unfolded polypeptides by the PPIase chaperone SlpALöw, Christian; Nordlund, Pär; Quistgaard, Esben M.
2018Modulation of protein-interaction states through the cell cycleDai, Lingyun; Zhao, Tianyun; Bisteau, Xavier; Sun, Wendi; Prabhu, Nayana; Lim, Yan Ting; Sobota, Radoslaw M.; Kaldis, Philipp; Nordlund, Pär
2016Molecular insights into substrate recognition and catalytic mechanism of the chaperone and FKBP peptidyl-prolyl isomerase SlyDQuistgaard, Esben M.; Weininger, Ulrich; Ural-Blimke, Yonca; Modig, Kristofer; Nordlund, Pär; Akke, Mikael; Löw, Christian
2019Monitoring structural modulation of redox-sensitive proteins in cells with MS-CETSASun, Wendi; Dai, Lingyun; Yu, Han; Puspita, Brenda; Zhao, Tianyun; Li, Feng; Tan, Justin L.; Lim, Yan Ting; Chen, Ming Wei; Sobota, Radoslaw M.; Tenen, Daniel G.; Prabhu, Nayana; Nordlund, Pär
2013Nanobody mediated crystallization of an archeal mechanosensitive channelMoberg, Per; Quistgaard, Esben M.; Löw, Christian; Yau, Yin Hoe; Pardon, Els; Jegerschöld, Caroline; Wåhlin, Lisa; Geifman-Shochat, Susana; Steyaert, Jan; Nordlund, Pär
2012Optimisation of over-expression in E. coli and biophysical characterisation of human membrane protein synaptogyrin 1Löw, Christian; Jegerschöld, Caroline; Kovermann, Michael; Moberg, Per; Nordlund, Pär
2012Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolismEgeblad, Louise; Welin, Martin; Flodin, Susanne; Gräslund, Susanne; Wang, Liya; Balzarini, Jan; Eriksson, Staffan; Nordlund, Pär
2017Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive statesChen, Dan; Jansson, Anna; Sim, Daniel; Larsson, Andreas; Nordlund, Pär
2014Structural and biochemical characterization of Human PR70 in isolation and in complex with the scaffolding subunit of protein phosphatase 2ADovega, Rebecca; Tsutakawa, Susan; Quistgaard, Esben M.; Anandapadamanaban, Madhanagopal; Löw, Christian; Nordlund, Pär
2013Structural and biophysical characterization of the cytoplasmic domains of human BAP29 and BAP31Löw, Christian; Moberg, Per; Guettou, Fatma; Maddi, Karthik; Nordlund, Pär; Quistgaard, Esben M.
2014Structural basis for PTPA interaction with the invariant C-terminal tail of PP2ALöw, Christian; Quistgaard, Esben M.; Kovermann, Michael; Anandapadamanaban, Madhanagopal; Balbach, Jochen; Nordlund, Pär
2015Structural biology of proteins involved in the replication of herpesvirusesHew, Kelly Kai Li