Browsing by Author Ong, Alan Ann Lerk

Showing results 1 to 8 of 8
Issue DateTitleAuthor(s)
 2019A disease-causing intronic point mutation C19G alters tau exon 10 splicing via RNA secondary structure rearrangementTan, Jiazi; Yang, Lixia; Ong, Alan Ann Lerk; Shi, Jiahao; Zhong, Zhensheng; Lye, Mun Leng; Liu, Shiyi; Lisowiec-Wachnicka, Jolanta; Kierzek, Ryszard; Roca, Xavier; Chen, Gang
 2019General recognition of U‑G, U‑A, and C‑G pairs by double-stranded RNA-binding PNAs incorporated with an artificial nucleobaseOng, Alan Ann Lerk; Toh, Desiree-Faye Kaixin; Patil, Kiran M.; Meng, Zhenyu; Yuan, Zhen; Krishna, Manchugondanahalli S.; Devi, Gitali; Haruehanroengra, Phensinee; Lu, Yunpeng; Xia, Kelin; Okamura, Katsutomo; Sheng, Jia; Chen, Gang
2019Incorporating G-C pair-recognizing Guanidinium into PNAs for sequence and structure specific recognition of dsRNAs over dsDNAs and ssRNAsKrishna, Manchugondanahalli S.; Wang, Zhenzhang; Zheng, Liangzhen; Bowry, Jogesh; Ong, Alan Ann Lerk; Mu, Yuguang; Prabakaran, Mookkan; Chen, Gang
2019Incorporating modified bases and base-backbone linkers into PNAs for targeting RNA secondary structuresOng, Alan Ann Lerk
2018Incorporating uracil and 5-halouracils into short peptide nucleic acids for enhanced recognition of A–U pairs in dsRNAsPatil, Kiran M.; Ong, Alan Ann Lerk; Krishna, Manchugondanahalli Shivakumar; Toh, Desiree-Faye Kaixin; Yuan, Zhen; Meng, Zhenyu; Shu, Zhiyu; Zhang, Haiping; Lu, Lanyuan; Lu, Yunpeng; Chen, Gang
2019RNA secondary structure-based design of antisense peptide nucleic acids for modulating disease-associated aberrant tau pre-mRNA alternative splicingOng, Alan Ann Lerk; Tan, Jiazi; Bhadra, Malini; Dezanet, Clément; Patil, Kiran M.; Chong, Mei Sian; Kierzek, Ryszard; Decout, Jean-Luc; Roca, Xavier; Chen, Gang
 2019Sequence- and structure-specific probing of RNAs by short nucleobase-modified dsRNA-binding PNAs incorporating a fluorescent light-up uracil analogKrishna, Manchugondanahalli Shivakumar; Toh, Desiree-Faye Kaixin; Meng, Zhenyu; Ong, Alan Ann Lerk; Wang, Zhenzhang; Lu, Yunpeng; Xia, Kelin; Prabakaran, Mookkan; Chen, Gang
 2019A short chemically modified dsRNA-Binding PNA (dbPNA) inhibits influenza viral replication by targeting viral RNA panhandle structureKesy, Julita; Patil, Kiran M.; Kumar, Subaschandrabose Rajesh; Shu, Zhiyu; Yong, Hui Yee; Zimmermann, Louis; Ong, Alan Ann Lerk; Toh, Desiree-Faye Kaixin; Krishna, Manchugondanahalli S.; Yang, Lixia; Decout, Jean-Luc; Luo, Dahai; Prabakaran, Mookkan; Chen, Gang; Kierzek, Elzbieta