Browsing by Author Kannan, Srinivasaraghavan


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Issue DateTitleAuthor(s)
2021A chemical biology approach reveals a dependency of glioblastoma on biotin distributionYoon, Jeehyun; Grinchuk, Oleg V.; Kannan, Srinivasaraghavan; Ang, Melgious Jin Yan; Li, Zhenglin; Tay, Emmy Xue Yun; Lok, Ker Zhing; Lee, Bernice Woon Li; Chuah, You Heng; Chia, Kimberly; Tirado-Magallanes, Roberto; Liu, Chenfei; Zhao, Haonan; Hor, Jin Hui; Lim, Jhin Jieh; Benoukraf, Touati; Toh, Tan Boon; Chow, Edward Kai-Hua; Kovalik, Jean-Paul; Ching, Jianhong; Ng, Shi-Yan; Koh, Ming Joo; Liu, Xiaogang; Verma, Chandra Shekhar; Ong, Derrick Sek Tong
2021Computational design of macrocyclic binders of S100B(ββ): novel peptide theranosticsKannan, Srinivasaraghavan; Aronica, Pietro G. A.; Nguyen, Thanh Binh; Li, Jianguo; Verma, Chandra Shekhar
2018Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocketKannan, Srinivasaraghavan; Venkatachalam, Gireedhar; Lim, Hong Hwa; Surana, Uttam; Verma, Chandra
2020Critical role for cold shock protein YB-1 in cytokinesisMehta, Sunali; Algie, Michael; Al-Jabry, Tariq; McKinney, Cushla; Kannan, Srinivasaraghavan; Verma, Chandra Shekhar; Ma, Weini; Zhang, Jessie; Bartolec, Tara K.; Masamsetti, V. Pragathi; Parker, Kim; Henderson, Luke; Gould, Maree L.; Bhatia, Puja; Harfoot, Rhodri; Chircop, Megan; Kleffmann, Torsten; Cohen, Scott B.; Woolley, Adele G.; Cesare, Anthony J.; Braithwaite, Antony
2020Dephosphorylation of YB-1 is required for nuclear localisation during G2 phase of the cell cycleMehta, Sunali; McKinney, Cushla; Algie, Michael; Verma, Chandra Shekhar; Kannan, Srinivasaraghavan; Harfoot, Rhodri; Bartolec, Tara K.; Bhatia, Puja; Fisher, Alistair J.; Gould, Maree L.; Parker, Kim; Cesare, Anthony J.; Cunliffe, Heather E.; Cohen, Scott B.; Kleffmann, Torsten; Braithwaite, Antony W.; Woolley, Adele G.
2023Disrupting the Dok3–Card9 interaction with synthetic peptides enhances antifungal effector functions of human neutrophilsLoh, Jia Tong; Teo, Joey Kay Hui; Kannan, Srinivasaraghavan; Verma, Chandra Shekhar; Lim, Hong-Hwa; Lam, Kong-Peng
 2023DOK3 promotes atopic dermatitis by enabling the phosphatase PP4C to inhibit the T cell signaling mediator CARD11Loh Jia Tong; Teo, Joey Kay Hui; Kannan, Srinivasaraghavan; Verma, Chandra Shekhar; Andiappan, Anand Kumar; Lim, Hong-Hwa; Lam, Kong-Peng
2023Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilitiesHo, Teresa Lai Fong; Lee, May Yin; Goh, Hui Chin; Ng, Germaine Yi Ning; Lee, Jane Jia Hui; Kannan, Srinivasaraghavan; Lim, Yan Ting; Zhao, Tianyun; Lim, Edwin Kok Hao; Phua, Cheryl Zi Jin; Lee, Yi Fei; Lim, Rebecca Yi Xuan; Ng, Perry Jun Hao; Yuan, Ju; Chan, Dedrick Kok Hong; Lieske, Bettina; Chong, Choon Seng; Lee, Kuok Chung; Lum, Jeffrey; Cheong, Wai Kit; Yeoh, Khay Guan; Tan, Ker Kan; Sobota, Radoslaw M.; Verma, Chandra Shekhar; Lane, David P.; Tam, Wai Leong; Venkitaraman, Ashok R.
2019The dual interactions of p53 with MDM2 and p300 : implications for the design of MDM2 inhibitorsKannan, Srinivasaraghavan; Partridge, Anthony William; Lane, David P.; Verma, Chandra Shekhar
2018Effects of single nucleotide polymorphisms on the binding of afatinib to EGFR : a potential patient stratification factor revealed by modeling studiesKannan, Srinivasaraghavan; Tan, Daniel Shao-Weng; Verma, Chandra Shekhar
 2023Elucidating the effect of polyethylene terephthalate chain structure on its enzymatic degradation behaviorLena, Jean-Baptiste; Gonçalves, Rui A.; Kharel, Sharad; Kannan, Srinivasaraghavan; Verma, Chandra Shekhar; Pinchi, Keerthi Mohan; Lim, Sierin; Lam, Yeng Ming
2022High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancerPalafox, Marta; Monserrat, Laia; Bellet, Meritxell; Villacampa, Guillermo; Gonzalez-Perez, Abel; Oliveira, Mafalda; Brasó-Maristany, Fara; Ibrahimi, Nusaibah; Kannan, Srinivasaraghavan; Mina, Leonardo; Herrera-Abreu, Maria Teresa; Òdena, Andreu; Sánchez-Guixé, Mònica; Capelán, Marta; Azaro, Analía; Bruna, Alejandra; Rodríguez, Olga; Guzmán, Marta; Grueso, Judit; Viaplana, Cristina; Hernández, Javier; Su, Faye; Lin, Kui; Clarke, Robert B.; Caldas, Carlos; Arribas, Joaquín; Michiels, Stefan; García-Sanz, Alicia; Turner, Nicholas C.; Prat, Aleix; Nuciforo, Paolo; Dienstmann, Rodrigo; Verma, Chandra Shekhar; Lopez-Bigas, Nuria; Scaltriti, Maurizio; Arnedos, Monica; Saura, Cristina; Serra, Violeta
2017Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinibKannan, Srinivasaraghavan; Pradhan, Mohan R.; Tiwari, Garima; Tan, Wei-Chong; Chowbay, Balram; Tan, Eng Huat; Tan, Daniel Shao-Weng; Verma, Chandra
2019Inhibiting S100B(ββ) for activating wild-type p53 : design of stapled peptidesKannan, Srinivasaraghavan; Aronica, Pietro G. A.; Tan, Yaw Sing; Verma, Chandra Shekhar
2019An inter-subunit protein-peptide interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone ReptinCoufalova, Dominika; Remnant, Lucy; Hernychova, Lenka; Muller, Petr; Healy, Alan; Kannan, Srinivasaraghavan; Westwood, Nicholas; Verma, Chandra Shekhar; Vojtesek, Borek; Hupp, Ted R.; Houston, Douglas R.
2023JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1Tabanifar, Bahareh; Moorthy, Anbalagan; Tsai, Heng Hang; Kannan, Srinivasaraghavan; Verma, Chandra Shekhar; Sabapathy, Kanaga
2016Long range recognition and selection in IDPs : the interactions of the C-terminus of p53Kannan, Srinivasaraghavan; Lane, David P.; Verma, Chandra Shekhar
 2014mAb806 binding to epidermal growth factor receptor: a computational studyNg, Yao Zong; Kannan, Srinivasaraghavan; Lane, David P.; Fuentes, Gloria; Verma, Chandra Shekhar
2022Molecular descriptors suggest stapling as a strategy for optimizing membrane permeability of cyclic peptidesLi, Jianguo; Kannan, Srinivasaraghavan; Aronica, Pietro; Brown, Christopher J.; Partridge, Anthony W.; Verma, Chandra Shekhar
2015Mussel adhesion is dictated by time-regulated secretion and molecular conformation of mussel adhesive proteinsPetrone, Luigi; Kumar, Akshita; Sutanto, Clarinda N.; Patil, Navinkumar J.; Kannan, Srinivasaraghavan; Palaniappan, Alagappan; Amini, Shahrouz; Zappone, Bruno; Verma, Chandra; Miserez, Ali