Showing results 1 to 20 of 45
next >
| Issue Date | Title | Author(s) |
 | 2021 | 2-Cyanoisonicotinamide Conjugation: A Facile Approach to Generate Potent Peptide Inhibitors of the Zika Virus Protease | Patil, Nitin A.; Quek, Jun-Ping; Schroeder, Barbara; Morewood, Richard; Rademann, Jörg; Luo, Dahai; Nitsche, Christoph |
| 2019 | Biocompatible macrocyclization between cysteine and 2-cyanopyridine generates stable peptide inhibitors | Nitsche, Christoph; Onagi, Hideki; Quek, Jun-Ping; Otting, Gottfried; Luo, Dahai; Huber, Thomas |
| 2016 | The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production | Chan, Kitti W. K.; Tay, Moon Y. F.; Smith, Kate; Ng, Ivan H. W.; Zhao, Yongqian; Ooi, Eng Eong; Lescar, Julien; Luo, Dahai; Jans, David A.; Forwood, Jade K.; Vasudevan, Subhash G. |
| 2014 | The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replication | Tay, Moon Y. F.; Saw, Wuan Geok; Zhao, Yongqian; Chan, Kitti W. K.; Singh, Daljit; Chong, Yuwen; Forwood, Jade K.; Ooi, Eng Eong; Grüber, Gerhard; Lescar, Julien; Luo, Dahai; Vasudevan, Subhash G. |
| | 2019 | Cell-active carbazole derivatives as inhibitors of the zika virus protease | Rassias, Gerasimos; Zogali, Vasiliki; Swarbrick, Crystall M. D.; Chan, Kitti Wing Ki; Chan, Shu Ann; Gwee, Chin Piaw; Wang, Sai; Kaplanai, Entzy; Canko, Aleksander; Kiousis, Dimitrios; Lescar, Julien; Luo, Dahai; Matsoukas, Minos-Timotheos; Vasudevan, Subhash G. |
| 2017 | Chikungunya virus nsP4 RNA-dependent RNA polymerase core domain displays detergent-sensitive primer extension and terminal adenylyltransferase activities | Chen, Ming Wei; Tan, Yaw Bia; Zheng, Jie; Zhao, Yongqian; Lim, Bee Ting; Cornvik, Tobias; Lescar, Julien; Ng, Lisa Fong Poh; Luo, Dahai |
| 2022 | A conserved arginine in NS5 binds genomic 3' stem-loop RNA for primer-independent initiation of flavivirus RNA replication | Wang, Sai; Chan, Kitti Wing Ki; Tan, Min Jie Alvin; Flory, Charlotte; Luo, Dahai; Lescar, Julian; Forwood, Jade K.; Vasudevan, Subhash G. |
| 2015 | A crystal structure of the dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication | Zhao, Yongqian; Soh, Tingjin Sherryl; Zheng, Jie; Chan, Kitti Wing Ki; Phoo, Wint Wint; Lee, Chin Chin; Tay, Moon Y. F.; Swaminathan, Kunchithapadam; Cornvik, Tobias Carl; Lim, Siew Pheng; Shi, Pei-Yong; Lescar, Julien; Vasudevan, Subhash G.; Luo, Dahai |
| 2022 | Crystal structure of the Rubella virus protease reveals a unique papain-like protease fold | Cheong, Ezekiel Ze Ken; Quek, Jun-Ping; Xin, Liu; Li, Chaoqiang; Chan, Jing Yi; Liew, Chong Wai; Mu, Yuguang; Zheng, Jie; Luo, Dahai |
| 2016 | Crystal structure of unlinked NS2B-NS3 protease from Zika virus | Zhang, Zhenzhen; Li, Yan; Loh, Ying Ru; Phoo, Wint Wint; Hung, Alvin W.; Kang, CongBao; Luo, Dahai |
| 2022 | Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold | Tan, Yaw Bia; Lello, Laura Sandra; Liu, Xin; Law, Yee-Song; Kang, Congbao; Lescar, Julien; Zheng, Jie; Merits, Andres; Luo, Dahai |
| | 2020 | Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3 | Phoo, Wint Wint; El Sahili, Abbas; Zhang, ZhenZhen; Chen, Ming Wei; Liew, Chong Wai; Lescar, Julien; Vasudevan, Subhash G.; Luo, Dahai |
| 2022 | Dynamic interactions of post cleaved NS2B cofactor and NS3 protease identified by integrative structural approaches | Quek, Jun-Ping; Ser, Zheng; Chew, Alvin Bing Liang; Li, Xin; Wang, Lili; Sobota, Radoslaw M.; Luo, Dahai; Phoo, Wint Wint |
| 2015 | The flavivirus NS2B–NS3 protease–helicase as a target for antiviral drug development | Luo, Dahai; Vasudevan, Subhash; Lescar, Julien |
| 2015 | Flexibility of NS5 Methyltransferase-Polymerase Linker Region Is Essential for Dengue Virus Replication | Zhao, Yongqian; Soh, Tingjin Sherryl; Chan, Kitti Wing Ki; Fung, Sarah Suet Yin; Swaminathan, Kunchithapadam; Lim, Siew Pheng; Shi, Pei-Yong; Huber, Thomas; Lescar, Julien; Luo, Dahai; Vasudevan, Subhash G. |
| 2014 | Functional interplay among the flavivirus NS3 protease, helicase, and cofactors | Li, Kuohan; Phoo, Wint Wint; Luo, Dahai |
| 2014 | High-resolution HDX-MS reveals distinct mechanisms of RNA recognition and activation by RIG-I and MDA5 | Liu, Chuan-Fa; Zheng, Jie; Yong, Hui Yee; Panutdaporn, Nantika; Tang, Kai; Luo, Dahai |
| 2020 | Identification and structural characterization of small molecule fragments targeting Zika virus NS2B-NS3 protease | Quek, Jun Ping; Liu, Shuang; Zhang, Zhenzhen; Li, Yan; Ng, Elizabeth Yihui; Loh, Ying Ru; Hung, Alvin W.; Luo, Dahai; Kang, CongBao |
| 2021 | Insights into the structure and RNA-binding specificity of Caenorhabditis elegans Dicer-related helicase 3 (DRH-3) | Li, Kuohan; Zheng, Jie; Wirawan, Melissa; Trinh, Nguyen Mai; Fedorova, Olga; Griffin, Patrick R.; Pyle, Anna M.; Luo, Dahai |
| 2021 | Interdomain flexibility of Chikungunya virus nsP2 helicase-protease differentially influences viral RNA replication and infectivity | Law, Yee-Song; Wang, Sainan; Tan, Yaw Bia; Shih, Orion; Utt, Age; Goh, Wei Yang; Lian, Bing-Jun; Chen, Ming Wei; Jeng, U-Ser; Merits, Andres; Luo, Dahai |
