Academic Profile : Faculty

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Asst Prof Shashi Bhushan
Assistant Professor, School of Biological Sciences
Professional Experience

Junior Group Leader, DFG Research Center for Experimental Biomedicine, University of Wuerzburg, Germany
Postdoctoral Studies, Gene Center, LMU Munich, Germany
We are interested in determining 3D structures of macromolecular protein complexes to understand their function and mechanism. We employ Cryo-Electron Microscopy with single particle reconstruction as our main tool for structural determination. Our laboratory is equipped with advanced Electron Microscopes and high speed computing clusters for routine single particle reconstruction work. We are mainly interested in following research areas:


Protein translocation across cellular membranes
Co-translational protein folding
Protein secretion
Translational stalling and regulation
 
  • Cooperative modulation of E. coli aquaporin water channel by cardiolipin: a new paradigm for allosteric control of multi-subunit membrane proteins.
  • Functional and structural characterization of an exemplar potassium ion channel from Mycobacterium tuberculosis
  • Mechanism and Compartmentalization of CbbQO-Type Rubisco Activases