Academic Profile : Faculty

Li-Hoi-Yeungv2.jpg picture
Assoc Prof Li Hoi Yeung
Associate Chair (Academic), School of Biological Science
Associate Professor, School of Biological Sciences
Co-Director, Nanyang Biologics-NTU Joint Laboratory for Drug Discovery and Therapeutics
 
External Links
 
Dec 2000: Ph.D. in Biochemistry, The Chinese University of Hong Kong

Aug 2000 – Dec 2004: Postdoctoral Fellow, Howard Hughes Medical Institute, Carnegie Institution of Washington, Baltimore, MD 21210, USA

Dec 2004 – 2010: Assistant Professor, School of Biological Sciences, Nanyang Technological University, Singapore

2010 - Present: Associate Professor, School of Biological Sciences, Nanyang Technological University, Singapore
1. Regulation of mitotic catastrophe
2. Regulation of spindle assembly and chromosome segregation.
3. Production of the RanGTP gradient in vivo.
4. Functional study of the RanGTPase in cell cycle progression.
5. Regulation of RCC1 during apoptosis
 
  • Characterization of DNA repair pathways in the regulation of H3K27ac-bound c-MYC, YY1 and CTCF-associated 3D genome organization loops in high-c-MYC myeloid leukemia
  • Divergent Synthesis of Pseudo-natural Product Covalent Inhibitors
  • Mechanistic insight of the novel sesquiterpene lactone, NYH002, in DNA damage repair inhibition and its potential in synthetic lethality-based cancer therapy.
  • Singapore found herbal medicine