Academic Profile : Faculty
Assoc Prof Koh Cheng Gee
Associate Chair (Faculty), School of Biological Sciences
Associate Professor, School of Biological Sciences
Email
External Links
Journal Articles
(Not applicable to NIE
staff as info will be
pulled from PRDS)
(Not applicable to NIE
staff as info will be
pulled from PRDS)
Highly Cited:
Manser, E., Loo, T. H., Koh, C. G., Zhao, Z. S., Chen, X. Q., Tan, L., ... & Lim, L. (1998). PAK kinases are directly coupled to the PIX family of nucleotide exchange factors. Molecular cell, 1(2), 183-192.
Chan, K. S., Koh, C. G., & Li, H. Y. (2012). Mitosis-targeted anti-cancer therapies: where they stand. Cell death & disease, 3(10), e411-e411.
Heng, Y. W., & Koh, C. G. (2010). Actin cytoskeleton dynamics and the cell division cycle. The international journal of biochemistry & cell biology, 42(10), 1622-1633.
Koh, C. G., Tan, E. J., Manser, E., & Lim, L. (2002). The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family. Current Biology, 12(4), 317-321.
Koh, C. G., Manser, E., Zhao, Z. S., Ng, C. P., & Lim, L. (2001). β1PIX, the PAK-interacting exchange factor, requires localization via a coiled-coil region to promote microvillus-like structures and membrane ruffles. Journal of cell science, 114(23), 4239-4251.
Hoon, J. L., Wong, W. K., & Koh, C. G. (2012). Functions and regulation of circular dorsal ruffles. Molecular and cellular biology, 32(21), 4246-4257.
Koh, C. G. (2006). Rho GTPases and their regulators in neuronal functions and development. Neurosignals, 15(5), 228-237.
Hoon, J. L., Tan, M. H., & Koh, C. G. (2016). The regulation of cellular responses to mechanical cues by Rho GTPases. Cells, 5(2), 17.
Lee, Y. P., Wong, C. H., Chan, K. S., Lai, S. K., Koh, C. G., & Li, H. Y. (2012). In vivo FRET imaging revealed a regulatory role of RanGTP in kinetochore-microtubule attachments via Aurora B kinase.
Wong, C. H., Chan, H., Ho, C. Y., Lai, S. K., Chan, K. S., Koh, C. G., & Li, H. Y. (2009). Apoptotic histone modification inhibits nuclear transport by regulating RCC1. nature cell biology, 11(1), 36-45.
Click here for more publications.
Recent Publications:
Sathe, S. R., Jain, D., Koh, C. G., & Yim, E. K. (2021). POPX2 phosphatase enhances topographical contact guidance for cell morphology and migration. Biomedical Materials, 16(2), 025020.
Khong, N. Z. J., Zeng, Y., Lai, S. K., Koh, C. G., Liang, Z. X., Chiam, K. H., & Li, H. Y. (2021). Dynamic swimming pattern of Pseudomonas aeruginosa near a vertical wall during initial attachment stages of biofilm formation. Scientific reports, 11(1), 1-11.
Kim, P. R., Zhang, S., Rahmat, M. B., & Koh, C. G. (2020). Partners in crime: POPX2 phosphatase and its interacting proteins in cancer. Cell death & disease, 11(10), 1-12.
Xing, Q. R., El Farran, C. A., Zeng, Y. Y., Yi, Y., Warrier, T., Gautam, P., ... & Loh, Y. H. (2020). Parallel bimodal single-cell sequencing of transcriptome and chromatin accessibility. Genome research, 30(7), 1027-1039.
Kim, P. R., Koon, Y. L., Lee, R. T. C., Azizan, F., Koh, D. H. Z., Chiam, K. H., & Koh, C. G. (2020). Phosphatase POPX2 interferes with cell cycle by interacting with Chk1. Cell Cycle, 19(4), 405-418.
Singh P, Gan CS, Guo T, Sze SK and Koh CG. (2011). Investigation of POPX2 phosphatase functions by comparative phosphoproteomic analysis. Proteomics, 11(14), 2891-2900.
Heng YW and Koh CG. (2010). Action Cytoskeleton Dynamics and the Cell Division Cycle. The International Journal of Biochemistry & Cell Biology, 42, 1622-1633.
Susila, A, Chan H, Loh AXW, HQ Phang, ET Wong, Tergaonkar V and Koh CG. (2010). POPX2 phosphatase regulates cancer cell motility and invasiveness. Cell Cycle, 9, 179-187.
Wong CH, Chan H, Ho CY, Lai SK, Chan KS, Koh CG* & Hoi-Yeung Li*. (2009). Apoptotic histone modification inhibits nuclear transport by regulating RCC1. Nature Cell Biology, 11, 36-45.
Xie Y, Tan EJ, Wee S, Manser E, Lim L, Koh CG. (2008). Functional interactions between phosphatase POPX2 and mDia modulate RhoA pathways. Journal of Cell Science, 121, 514-521.
Manser, E., Loo, T. H., Koh, C. G., Zhao, Z. S., Chen, X. Q., Tan, L., ... & Lim, L. (1998). PAK kinases are directly coupled to the PIX family of nucleotide exchange factors. Molecular cell, 1(2), 183-192.
Chan, K. S., Koh, C. G., & Li, H. Y. (2012). Mitosis-targeted anti-cancer therapies: where they stand. Cell death & disease, 3(10), e411-e411.
Heng, Y. W., & Koh, C. G. (2010). Actin cytoskeleton dynamics and the cell division cycle. The international journal of biochemistry & cell biology, 42(10), 1622-1633.
Koh, C. G., Tan, E. J., Manser, E., & Lim, L. (2002). The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family. Current Biology, 12(4), 317-321.
Koh, C. G., Manser, E., Zhao, Z. S., Ng, C. P., & Lim, L. (2001). β1PIX, the PAK-interacting exchange factor, requires localization via a coiled-coil region to promote microvillus-like structures and membrane ruffles. Journal of cell science, 114(23), 4239-4251.
Hoon, J. L., Wong, W. K., & Koh, C. G. (2012). Functions and regulation of circular dorsal ruffles. Molecular and cellular biology, 32(21), 4246-4257.
Koh, C. G. (2006). Rho GTPases and their regulators in neuronal functions and development. Neurosignals, 15(5), 228-237.
Hoon, J. L., Tan, M. H., & Koh, C. G. (2016). The regulation of cellular responses to mechanical cues by Rho GTPases. Cells, 5(2), 17.
Lee, Y. P., Wong, C. H., Chan, K. S., Lai, S. K., Koh, C. G., & Li, H. Y. (2012). In vivo FRET imaging revealed a regulatory role of RanGTP in kinetochore-microtubule attachments via Aurora B kinase.
Wong, C. H., Chan, H., Ho, C. Y., Lai, S. K., Chan, K. S., Koh, C. G., & Li, H. Y. (2009). Apoptotic histone modification inhibits nuclear transport by regulating RCC1. nature cell biology, 11(1), 36-45.
Click here for more publications.
Recent Publications:
Sathe, S. R., Jain, D., Koh, C. G., & Yim, E. K. (2021). POPX2 phosphatase enhances topographical contact guidance for cell morphology and migration. Biomedical Materials, 16(2), 025020.
Khong, N. Z. J., Zeng, Y., Lai, S. K., Koh, C. G., Liang, Z. X., Chiam, K. H., & Li, H. Y. (2021). Dynamic swimming pattern of Pseudomonas aeruginosa near a vertical wall during initial attachment stages of biofilm formation. Scientific reports, 11(1), 1-11.
Kim, P. R., Zhang, S., Rahmat, M. B., & Koh, C. G. (2020). Partners in crime: POPX2 phosphatase and its interacting proteins in cancer. Cell death & disease, 11(10), 1-12.
Xing, Q. R., El Farran, C. A., Zeng, Y. Y., Yi, Y., Warrier, T., Gautam, P., ... & Loh, Y. H. (2020). Parallel bimodal single-cell sequencing of transcriptome and chromatin accessibility. Genome research, 30(7), 1027-1039.
Kim, P. R., Koon, Y. L., Lee, R. T. C., Azizan, F., Koh, D. H. Z., Chiam, K. H., & Koh, C. G. (2020). Phosphatase POPX2 interferes with cell cycle by interacting with Chk1. Cell Cycle, 19(4), 405-418.
Singh P, Gan CS, Guo T, Sze SK and Koh CG. (2011). Investigation of POPX2 phosphatase functions by comparative phosphoproteomic analysis. Proteomics, 11(14), 2891-2900.
Heng YW and Koh CG. (2010). Action Cytoskeleton Dynamics and the Cell Division Cycle. The International Journal of Biochemistry & Cell Biology, 42, 1622-1633.
Susila, A, Chan H, Loh AXW, HQ Phang, ET Wong, Tergaonkar V and Koh CG. (2010). POPX2 phosphatase regulates cancer cell motility and invasiveness. Cell Cycle, 9, 179-187.
Wong CH, Chan H, Ho CY, Lai SK, Chan KS, Koh CG* & Hoi-Yeung Li*. (2009). Apoptotic histone modification inhibits nuclear transport by regulating RCC1. Nature Cell Biology, 11, 36-45.
Xie Y, Tan EJ, Wee S, Manser E, Lim L, Koh CG. (2008). Functional interactions between phosphatase POPX2 and mDia modulate RhoA pathways. Journal of Cell Science, 121, 514-521.
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