Academic Profile : Faculty
Assoc Prof Roderick Wayland Bates
Research Integrity Officer
Associate Professor, School of Chemistry, Chemical Engineering and Biotechnology
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Roderick Bates received his PhD at Imperial College, London with Professor Steven Ley, using organoiron complexes for organic synthesis. After a postdoctoral stint at Colorado State University with Professor L. S. Hegedus working on chromium carbenes, he moved to the University of North Texas as an Assistant Professor. After some years spent in Thailand at Chulalongkorn University and the Chulabhorn Research Institute and a short stay in the ill-fated Department of Chemistry at Exeter in England, he joined Nanyang Technological University as a pioneer member of the Division of Chemistry and Biological Chemistry. He is currently an Associate Professor and a Fellow of NTU’s Teaching Excellence Academy. Since April 1st, 2018, he has been serving as the University's Research Integrity Officer. He has research interests are in the use of transition metals in organic synthesis, stereocontrol in natural product synthesis and drug discovery. His book “Organic Synthesis using Transition Metals” (2nd Ed.) was published by Wiley in April 2012. He is also a lecturer on Forensic Science for a Coursera MOOC.
Alkaloid synthesis
Natural Product Synthesis
Stereochemistry
Drug Discovery
Correcting the Natural Product Literature
Natural Product Synthesis
Stereochemistry
Drug Discovery
Correcting the Natural Product Literature
- A unique role for ABCB1/MDR1 in tumor suppression and its application to overcome drug resistance in cancer
- Synthesis of Novel and Complex Molecules through Selective Coupling
- Identifying novel targets and designing new anti-TB agents through understanding the Mycobacterial stringent response to stress
- Project 3: Exploratory chemistry
- Targeting energy of life for the development of drug combination to eradicate antibiotic-tolerant Mycobacterium abscessus, a clinical nightmare
US 2020/0231550 A1: Compounds for Treating Tuberculosis (2021)
Abstract: The present invention relates to pyrimidine compounds and compositions for treating tuberculosis. These compounds may be used to target the F1 domain of F-ATP synthase and may be used with bedaquiline or 6-chloro-2-ethyl-N-[[4-[4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide (Q203) or a combination thereof.
Abstract: The present invention relates to pyrimidine compounds and compositions for treating tuberculosis. These compounds may be used to target the F1 domain of F-ATP synthase and may be used with bedaquiline or 6-chloro-2-ethyl-N-[[4-[4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide (Q203) or a combination thereof.
Awards
Nanyang Teaching Excellence Award 2006, 2010
Fellowships & Other Recognition
Fellow of the NTU Teaching Excellence Academy
Courses Taught
Forensic Science - this is an introductory course to Forensic Science taught to give students a general idea of this eternally topical subject, illustrated with real cases. The course is taught in a hybrid mode.
Metal Mediated Reactions - this is a year 4 courses to show how metal mediated reactions, especially those using catalysis, can be used to make the organic molecules that impact our lives and our economy.
Chemical Sustainability - An Asian perspective - a course co-taught with IIT Madras and Chulalongkorn University and taken by students from all three institutions examining multiple aspects of sustainability
Metal Mediated Reactions - this is a year 4 courses to show how metal mediated reactions, especially those using catalysis, can be used to make the organic molecules that impact our lives and our economy.
Chemical Sustainability - An Asian perspective - a course co-taught with IIT Madras and Chulalongkorn University and taken by students from all three institutions examining multiple aspects of sustainability
Supervision of PhD Students
Teo Hong Kang