Academic Profile

BSc, 2002 – 2006, Ph.D. 2006 - 2010, NTU, Singapore.
Associate Professor, 2019 - Present, LKCMedicine, NTU, Singapore.
Nanyang Assistant Professor, 2013-2019, LKCMedicine, NTU, Singapore.
Postdoctoral Fellow, 2010-2013, HHMI/Yale University, USA.
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Assoc Prof Luo Dahai
Associate Professor, Infection and Immunity, Lee Kong Chian School of Medicine
Associate Professor, Lee Kong Chian School of Medicine

My lab studies the molecular events involved in the battle between host and pathogens, in particular between RNA viruses and humankind. Using various methods ranging from biochemistry, biophysics, structural biology, and cell biology, we successfully answered interesting and demanding questions in the fields of viral replication and host defense systems. Our long-term goal is to better understand the conflict between host and pathogens and improve the well-being of humankind. My lab’s research focuses on the following two interrelated directions: 1) RNA virus transcription, replication, and the generation of pathogenic RNA species; 2) Host defense mechanisms involved in pathogenic RNA sensing and processing. We would like to exercise molecular engineering targeting RNA and RNA-protein complexes to develop new methods and tools for research and therapies.
  • Development of immune-modulatory RNAs to regulate RIG-Imediated antiviral immune response for therapy andvaccination

  • Dissecting the Chikungunya Virus RNA Replication Process in vitro and in Live Cells

  • Fighting for Better Survival: Viral RNA Biogenesis versus Host Defense

  • Fluorescence-enhanced microarray for high-throughput detection of SARS-CoV-2 antigens and neutralizing antibodies

  • Provost's Chair in Medicine (Luo Dahai)

  • Studying Zika Virus Pathogenesis and the Development ofTherapeutics, in vitro Cell Culture Model and Mouse Modelthat Display Various Diseases Phenotypes