Academic Profile : Faculty

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Assoc Prof Luo Dahai
Associate Professor, Infection and Immunity, Lee Kong Chian School of Medicine
Provost’s Chair in Medicine
Associate Professor, Lee Kong Chian School of Medicine
BSc, 2002 – 2006, Ph.D. 2006 - 2010, NTU, Singapore.
Associate Professor, 2019 - Present, LKCMedicine, NTU, Singapore.
Nanyang Assistant Professor, 2013-2019, LKCMedicine, NTU, Singapore.
Postdoctoral Fellow, 2010-2013, HHMI/Yale University, USA.
Our lab is deeply engaged in studying the molecular interactions between RNA viruses and their human hosts. We employ a range of scientific methods, including biochemistry, biophysics, structural biology, and cell biology, to explore this critical area. Our work has led to significant insights into the mechanisms of viral replication and the complexities of the host's defense systems. These studies are more than academic pursuits; they are essential steps toward a greater understanding of viral-host dynamics.

Our long-term objective is to deepen our understanding of the interaction between hosts and pathogens. This knowledge is crucial for the development of more effective antiviral strategies and for improving human health. By comprehensively analyzing these interactions, we aim to contribute to the advancement of medical science and the enhancement of human well-being, confronting one of the most persistent challenges in human health.
  • Decoding the Membrane-Associated Assembly of Viral Replication Complex in Live Cells Using Nanotopography Engineering
  • Delivery of 5' triphosphate modified RNAs using extracellular vesicles for cancer immunotherapy
  • Development a novel self-amplifying RNA vector for mRNA vaccine development against infectious diseases and cancers
  • Dissecting the Chikungunya Virus RNA Replication Process in vitro and in Live Cells
  • Fighting for Better Survival: Viral RNA Biogenesis versus Host Defense
  • Identification of Structural and Functional roles of RNA in TNFR Signaling: Key for Designing Next Generation Drugs for Cancers and Immune Disorders
  • Midwest AViDD Center Programme
  • Molecular Understanding of the Rubella Virus Replication Process
  • Provost's Chair in Medicine (Luo Dahai)
  • Simultaneous inhibition of mutant KRAS and activation of RIG-I pathway for the treatment of pancreatic cancer
2021 LKCMedicine Dean’s Award for Research
2019 –2024 Provost’s Chair in Medicine
2018 The Nanyang Research Award (Young Investigator). Nanyang Technological University, Singapore.
2018 - 2022 EMBO Young Investigator Award. The European Molecular Biology Organization.
Fellowships & Other Recognition
2010 – 2013 Research Associate Fellowship, Howard Hughes Medical Institute, USA.