Academic Profile

Team

• Dr Seow Theng Ong, PhD, Senior Research Fellow
• Dr Mobashar Hussain Urf Turabe Fazil, PhD, Research Fellow
• Dr Madhavi Latha Somaraju Chalasani, PhD, Research Fellow
• Ms Praseetha Rajesh Chandramohanadas, Research Assistant
• Mr Atish Kizhakeyil, PhD student

Assistant Professor Navin Kumar Verma is an Assistant Professor of Immunology and Cell Biology at the Lee Kong Chian School of Medicine, Nanyang Technological University. He obtained a PhD in Clinical Medicine from Trinity College Dublin (TCD), Ireland’s most prestigious University. He then undertook postdoctoral research training at the Institute of Molecular Medicine, TCD, where he studied the integrin LFA-1-mediated signalling pathways involved in T-cell migration and effector functions. He was trained in various aspects of Immunology, Cell Biology, Hematolymphoid Malignancies and Nanomedicine.

Asst Prof Verma has made significant contribution in the area of lymphocyte signalling. He has published more than 45 peer-reviewed papers which are widely cited (h-Index 17) in the fields of immunology, cell biology, cell signalling, pharmacology, toxicology and nanomedicine. In a recent ground-breaking discovery, his research team demonstrated a novel gene silencing technique applied to primary human T-lymphocytes using molecularly-targeted GapmeR. He is the co-author of eight patents.

Asst Prof Verma has received several awards and prizes for his scientific achievements. These include the Glory of India Award, SERS Fellow, best presentation awards at scientific conferences and the first prize for outstanding business plan of his research in the Trinity Heat of Idea to Product (I2P) coordinated by the University of Texas at Austin I2P® Program. He has served as a reviewer for national and international research grants and scientific journals.
Asst Prof Navin Verma.jpg picture
Asst Prof Navin Kumar Verma
Assistant Professor, Immunology and Cell Biology, Lee Kong Chian School of Medicine
Assistant Professor, Lee Kong Chian School of Medicine
Postgraduate Tutor, Lee Kong Chian School of Medicine (LKCMedicine)

The main research interest of the lab is centred on developing new ways to treat immune-mediated inflammatory disorders (e.g. rheumatoid arthritis, psoriasis), skin diseases (e.g. melasma, atopic dermatitis), superficial infections (e.g. skin/wound infections) and cancer (hematolymphoid malignancies). His research team employs cutting-edge tools and advanced technologies to understand disease mechanisms at subcellular and molecular levels using various in vitro and in vivo model systems.

Research in Asst Prof Verma’s lab is focused on the following major multidisciplinary projects:

1. Elucidation of molecular processes mediated via adhesion receptors in lymphocytes; in particular, biological roles and functional significance of the integrin LFA-1 and associated signaling and adaptor proteins in T-cell migration.
2. Identification of signaling protein interactome involved in the active locomotion of T-lymphocytes.
3. Characterization of inflammatory skin disorders for biomarker discovery.
4. Development of novel gene silencing-based therapeutic strategy that could be combined with nanotechnology enabled controlled-release drug delivery systems for targeting skin diseases, hematolymphoid malignancies and other cancer, in addition to immunotherapeutic applications.
5. Exploitation of the anti-inflammatory and anti-infective properties of multi-functional bioactive peptides/polymers for treating superficial infections and wound applications.

Research goal

Research goal
 
  • Characterization of Peripheral Blood and Cerebrospinal Fluid Lymphocytes in Alzheimer’s Disease

  • Evaluation of N-WASP Inhibitors in Promoting Wound Healing

  • Inhalable Muco-Penetrative GapmeR Cocktail Targeting SARS-CoV-2 and Potential Variants

  • Role of Microbiota in Cancer resistance of N-WASP Knockout mice

  • Singapore IYMPHoma translatiONal StudY (SYMPHONY)