Academic Profile : Faculty
Prof Duan Hongwei
Assistant Chair (Research & Graduate Education), School of Chemistry, Chemical Engineering and Biotechnology
Professor, School of Chemistry, Chemical Engineering and Biotechnology
Email
Controlled Keywords
User Keywords (optional)
Dr. Duan received his B.S. and M.S. degrees from Fudan University in Chemistry and Macromolecular Sciences. He completed his PhD in Physical Chemistry at Max Planck Institute of Colloids and Interfaces and Postdam University in 2005. After that, he moved to the Department of Biomedical Engineering at Emory University and Georgia Institute of Technology for his postdoctoral training. Before joining the School of Chemical and Biomedical Engineering as a Nanyang Assistant Professor in 2009, he was an Assistant Professor (research track) in Biomedical Engineering at Emory University. He was promoted to Associate Professor with tenure in 2015 and to Professor in 2020.
His current research focuses on understanding surface/interface properties of microscale and nanoscale colloidal particles to achieve tailored optical, electronic, magnetic, catalytic, and structural properties, and exploring their biomedical and environmental applications. He is particularly interested in new chemistry towards nanostructures with structurally integrated inorganic nanocrystals and polymers and new approaches towards well-defined multifunctional assemblies of nanoscale building blocks. The key research topics in his lab include: Plasmonics and Surface-Enhanced Optical Properties; Interfacial Assembly of Colloidal Particles; In Vitro Diagnostics; Detection and Treatment of Antimicrobial Resistance; Controlled Delivery of Biologics.
- Dynamic Metal-Enhanced Fluorescence Microarray for Ultrasensitive Detection of Neurodegenerative Disease Biomarkers
- Mussel-Inspired Antifouling Coating for Liquid Separation in Biphasic Biocatalytic Reactions
- Development of Functional Nanoparticles Based In Vitro Diagnostics
- Development of Lateral Flow Assay for Rapid Identification and Susceptibility Testing of Antimicrobial Resistance Bacteria
- Ultrasonic Imprinting of Plasmonic Nanostructures for Surface-Enhanced Raman Spectroscopy
- Platform Technology for Bacterial Surface Modification and Rapid Detection of Antimicrobial-Resistant Bacteria
- NIR-activable In-situ Production of C-di-GMP as a STING Agonist for Cancer Immunotherapy
- Biodegradable Polyion Complex of Cationic Antimicrobial Peptides for Safe Antibacterial Therapy
- Combating Multidrug-resistant Gram-negative Bacteria with Cyclic and Acyclic Glycopeptides
- Metabolic Labeling Mediated Biofilm Analysis and Rapid Antimicrobial Susceptibility Testing
US 2019/0366733 A1: A Process For Isotropic Structural Colour Printing And An Apparatus For Detecting A Target Substance In The Gaseous Phase (2021)
Abstract: According to the present disclosure, an isotropic structural colour printing process is provided. The process comprising (a) providing an ink composition comprising ink particles (such as polymeric particles (e.g. polystyrene), metal-organic frameworks (MOFs) (e.g. ZIF-8)) in a liquid reagent; and (b) depositing the ink composition onto a surface of a substrate (e.g. anodic aluminium oxide membrane, photo papers). Due to capillary action and/or absorption of the liquid reagent, the ink particles form an amorphous arrangement of structures that lead to isotropic structural colour. In the preferred embodiment, the ink particles may further be coated with a catechol group (such as polydopamine). An apparatus for detecting a target substance in the gaseous phase, wherein the apparatus comprises a nanostructure capable of exhibiting a change in isotropic structural colour when one or more molecules of the target substance are entrapped as an indication that the target substance is present, is also provided.
US 2017/0304796 A1: Method For Preparing A Magnetic Chain Structure (2021)
Abstract: A method for preparing a magnetic chain structure is provided. The method comprises providing a plurality of magnetic particles; dispersing the plurality of magnetic particles in a solution comprising a dopamine-based material to form a reaction mixture; applying a magnetic field across the reaction mixture to align the magnetic particles in the reaction mixture; and polymerizing the dopamine-based material on the aligned magnetic particles to obtain the magnetic chain structure. A magnetic chain structure prepared by the method is also provided.
US 2022/0332892 A1: β-Peptido-Sugar-Copolymer (2024)
Abstract: There is provided a β-peptido sugar-copolymer having the structure of formula (I) as defined herein, or a stereoisomer, a tautomer, an N-oxide, a hydrate, a solvate, or a salt thereof, or a mixture of the same. There is provided a process to make the β-peptido sugar-copolymer as defined herein. There are further provided medical applications of the β-peptido sugar-copolymer as defined herein. In a preferred embodiment, a block-like copolymer poly(amido-D-glucose)-block-poly-β-(L)-homolysine (PDGu-b-PBLK) synthesized via anionic ring-opening polymerization (ROP) demonstrates an antimicrobial efficacy, an enhanced selectivity towards different bacteria, biocompatibility vs. mammalian cells and spontaneous assembly.
Abstract: According to the present disclosure, an isotropic structural colour printing process is provided. The process comprising (a) providing an ink composition comprising ink particles (such as polymeric particles (e.g. polystyrene), metal-organic frameworks (MOFs) (e.g. ZIF-8)) in a liquid reagent; and (b) depositing the ink composition onto a surface of a substrate (e.g. anodic aluminium oxide membrane, photo papers). Due to capillary action and/or absorption of the liquid reagent, the ink particles form an amorphous arrangement of structures that lead to isotropic structural colour. In the preferred embodiment, the ink particles may further be coated with a catechol group (such as polydopamine). An apparatus for detecting a target substance in the gaseous phase, wherein the apparatus comprises a nanostructure capable of exhibiting a change in isotropic structural colour when one or more molecules of the target substance are entrapped as an indication that the target substance is present, is also provided.
US 2017/0304796 A1: Method For Preparing A Magnetic Chain Structure (2021)
Abstract: A method for preparing a magnetic chain structure is provided. The method comprises providing a plurality of magnetic particles; dispersing the plurality of magnetic particles in a solution comprising a dopamine-based material to form a reaction mixture; applying a magnetic field across the reaction mixture to align the magnetic particles in the reaction mixture; and polymerizing the dopamine-based material on the aligned magnetic particles to obtain the magnetic chain structure. A magnetic chain structure prepared by the method is also provided.
US 2022/0332892 A1: β-Peptido-Sugar-Copolymer (2024)
Abstract: There is provided a β-peptido sugar-copolymer having the structure of formula (I) as defined herein, or a stereoisomer, a tautomer, an N-oxide, a hydrate, a solvate, or a salt thereof, or a mixture of the same. There is provided a process to make the β-peptido sugar-copolymer as defined herein. There are further provided medical applications of the β-peptido sugar-copolymer as defined herein. In a preferred embodiment, a block-like copolymer poly(amido-D-glucose)-block-poly-β-(L)-homolysine (PDGu-b-PBLK) synthesized via anionic ring-opening polymerization (ROP) demonstrates an antimicrobial efficacy, an enhanced selectivity towards different bacteria, biocompatibility vs. mammalian cells and spontaneous assembly.
Courses Taught
BG4215 Biomedical Nanotechnology
CH5204 Quality Systems Operations
CH5204 Quality Systems Operations