Academic Profile : Faculty
Assoc Prof Tan Meng How
Associate Professor, School of Chemistry, Chemical Engineering and Biotechnology
Deputy Director (Undergraduate) and REP Fellow, School of Chemistry, Chemical Engineering and Biotechnology (CCEB)
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Dr. Meng How Tan received his B.S. degree in mechanical engineering and B.A. degree in economics from University of California - Berkeley, his M.S. degree in aeronautics from California Institute of Technology, his M.S. degree in biomedical engineering from NTU, and his Ph.D. in developmental biology from Stanford University. He then performed postdoctoral research at Stanford University with Jin Billy Li, Mylene Yao, and Wing Hung Wong. Subsequently, he joined NTU as an Assistant Professor in 2014 and was promoted to an Associate Professor with tenure in 2021. He was previously Associate Chair (Students & Continuing Education) in the School of Chemistry, Chemical Engineering and Biotechnology (CCEB) and is currently Deputy Director (Undergraduate) of the Renaissance Engineering Programme (REP), one of the Premier Scholars Programmes in NTU. His laboratory works actively in the field of nucleic acid editing. To date, he has published multiple papers in top academic journals, such as Nature, Nature Biotechnology, Nature Methods, Nature Chemical Biology, and Nature Communications. He received the Outstanding Young Principal Investigator Award from The American Institute of Chemical Engineers – Singapore Local Section (AIChE-SLS) in 2019 and was named an EMBO Global Investigator in 2020.
Meng How’s overall research goal is to advance the field of nucleic acid editing. His lab seeks to (1) develop new genome and transcriptome engineering tools, including CRISPR-based technologies, for synthetic biology applications, and (2) gain fundamental insights into the ADAR family of enzymes, which are essential proteins involved in RNA editing.
- A Sustainable Bio-platform for High Quality Microbial Protein Production (SCBE-TMH_NEW)
- A Sustainable Bio-platform for High Quality Microbial Protein Production
- Codebooks for Data Reconstruction with Biological Applications
- Development of new prime editors for precision genome engineering
- Towards direct and rapid mapping of RNA modifications with nanopore sequencing
- Deep learning to understand the interplay between RNA editing and splicing in healthy and disease states
- Frontiers in Genome and Transcriptome Engineering
- Elucidating the RNA editing landscape in single animal cells
- EMBO Global Investigator Network (GIN)
- iPSCs-differentiated Natural Killer cells for cancer immunotherapies (Panakeia)
- RNA.
Research and Non-traditional experiments in the Arts—design, and sciences—concentrating on the study of RNA Modifications, Viruses, and Imaging Technologies. - Characterization of a novel Cas13-based RNA engineering technology
- Generation of Extracellular Matrix Fibroblast Reporter Cell Lines via CRISPR-Cas based Genomic Engineering
- The eMEASURE-RNA Initiative: Exploring the Molecular Basis of RNA Editing, Sensing and Immune Response – New Approaches for Immuno- Oncology Therapy (NTU PI: Luo Dahai)
- The eMEASURE-RNA Initiative: Exploring the Molecular Basis of RNA Editing, Sensing and Immune Response – New Approaches for Immuno- Oncology Therapy (NTU PI: Tan Meng How)
- Enhancing CRISPR-mediated homology directed repair in human cells with yeast DNA repair proteins
Awards
2019 Outstanding Young Principal Investigator Award from The American Institute of Chemical Engineers – Singapore Local Section (AIChE-SLS)
2020 European Molecular Biology Organization (EMBO) Global Investigator
2020 European Molecular Biology Organization (EMBO) Global Investigator