Academic Profile

Chew Sing Yian is an Associate Professor at the School of Chemical & Biomedical Engineering, and Lee Kong Chian School of Medicine. 

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Assoc Prof Chew Sing Yian
Associate Professor, Lee Kong Chian School of Medicine
Associate Professor, School of Chemical and Biomedical Engineering

Biofunctional micro-/ nano-structured scaffolds for tissue engineering applications; Electrospinning; Cellular responses to micro- /nano-structured scaffolds; Neural tissue engineering

 
  • Antimicrobial Polymeric Nanoparticles with Good Efficacy ina Complex Environment

  • Engineering Scaffold-Mediated Neural Cell Therapy for Spinal Cord Injury Treatment

  • Engineering Scaffold-Mediated Neural Cell Therapy for Spinal Cord Injury Treatment (Astar)

  • Engineering Scaffold-Mediated Neural Cell Therapy for Spinal Cord Injury Treatment (CNRS @ CREATE)

  • Engineering Scaffold-Mediated Neural Cell Therapy for Spinal Cord Injury Treatment (NTU)

  • Engineering Scaffold-Mediated Neural Cell Therapy for Spinal Cord Injury Treatment (SMART CAMP)

  • Establishing a stroke model & regenerative treatment approach

  • Establishing neural cell membrane-coated particles for enhanced drug/gene delivery in the nervous system

  • High Throughput Label-Free Flow Cytometry Based On Multiplex Raman Spectroscopy

  • Radio frequency encoding ultrafast optical spectrometer and its demonstration in flow cytometry

  • Synthetic collagen peptide biomaterials for drug/gene delivery in nerve repair
 
  • William Ong, Nicolas Marinval, Junquan Lin, Mui Hoon Nai, Yee‐Song Chong, Coline Pinese, Sreedharan Sajikumar, Chwee Teck Lim, Charles Ffrench‐Constant, Marie E. Bechler, Sing Yian Chew (2020), 'Biomimicking Fiber Platform with Tunable Stiffness to Study Mechanotransduction Reveals Stiffness Enhances Oligodendrocyte Differentiation but Impedes Myelination through YAP‐Dependent Regulation', Small, https://doi.org/10.1002/smll.202003656


  • Kunyu Zhang, Wai Hon Chooi, Shuang Liu, Jiah Shin Chin, Aoife Murray, Dean Nizetic, Du Cheng and Sing Yian Chew (2020), 'Localized delivery of CRISPR/dCas9 via layer-by-layer self-assembling peptide coating on nanofibers for neural tissue engineering', Biomaterials, 256, pp. 120225, https://doi.org/10.1016/j.biomaterials.2020.120225


  • U Milbreta, J Q Lin, C Pinese, W Ong, J S Chin, H Shirahama, R Mi, A Williams, M E Bechler, J Wang, C french-Constant, A Hoke, S Y Chew (2018), 'Scaffold-mediated sustained, non-viral delivery of miR-219/miR-338 promotes CNS remyelination', Molecular Therapy, 27 (2), pp. 411-423, https://doi.org/10.1016/j.ymthe.2018.11.016


  • Na Zhang, U Milbreta, J S Chin, C Pinese, J Q Lin, H Shirahama, W Jiang, H Liu, R Mi, A Hoke, WT Wu, S Y Chew (2019), 'Biomimicking Fiber Scaffold as an Effective In Vitro and In Vivo MicroRNA Screening Platform for Directing Tissue Regeneration', Advanced Science, 6 (9), pp. 1800808, https://doi.org/10.1002/advs.201800808