Academic Profile : Faculty

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Assoc Prof Chew Sing Yian
Associate Professor, School of Chemistry, Chemical Engineering and Biotechnology
Associate Professor, Lee Kong Chian School of Medicine
Associate Professor, School of Materials Science & Engineering (Courtesy Appointment)
External Links
Journal Articles
(Not applicable to NIE
staff as info will be
pulled from PRDS)
Highly Cited:
Chew, S. Y., Wen, J., Yim, E. K., & Leong, K. W. (2005). Sustained release of proteins from electrospun biodegradable fibers. Biomacromolecules, 6(4), 2017-2024.

Chew, S. Y., Mi, R., Hoke, A., & Leong, K. W. (2008). The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation. Biomaterials, 29(6), 653-661.

Chew, S. Y., Mi, R., Hoke, A., & Leong, K. W. (2007). Aligned protein–polymer composite fibers enhance nerve regeneration : a potential tissue‐engineering platform. Advanced Functional Materials, 17(8), 1288-1296.

Jiang, X., Lim, S. H., Mao, H. Q., & Chew, S. Y. (2010). Current applications and future perspectives of artificial nerve conduits. Experimental Neurology, 223(1), 86-101.

Cao, H., Liu, T., & Chew, S. Y. (2009). The application of nanofibrous scaffolds in neural tissue engineering. Advanced Drug Delivery Reviews, 61(12), 1055-1064.

Chew, S. Y., Wen, Y., Dzenis, Y., & Leong, K. W. (2006). The role of electrospinning in the emerging field of nanomedicine. Current Pharmaceutical Design, 12(36), 4751-4770.

Cao, H., Mchugh, K., Chew, S. Y., & Anderson, J. M. (2010). The topographical effect of electrospun nanofibrous scaffolds on the in vivo and in vitro foreign body reaction. Journal of Biomedical Materials Research Part A: An Official Journal of The Society for Biomaterials, The Japanese Society for Biomaterials, and The Australian Society for Biomaterials and the Korean Society for Biomaterials, 93(3), 1151-1159.

Liao, I. C., Chew, S. Y., & Leong, K. W. (2006). Aligned core–shell nanofibers delivering bioactive proteins. Nanomedicine, 1(4), 465-471.

Chew, S. Y., Hufnagel, T. C., Lim, C. T., & Leong, K. W. (2006). Mechanical properties of single electrospun drug-encapsulated nanofibres. Nanotechnology, 17(15), 3880.

Zhuang, P., Sun, A. X., An, J., Chua, C. K., & Chew, S. Y. (2018). 3D neural tissue models : from spheroids to bioprinting. Biomaterials, 154, 113-133.

Click here for more publications.

Recent Publication:
Zhang, N., Lin, J., Chin, J. S., Wiraja, C., Xu, C., McGrouther, D. A., & Chew, S. Y. (2022). Delivery of Wnt inhibitor WIF1 via engineered polymeric microspheres promotes nerve regeneration after sciatic nerve crush. Journal of Tissue Engineering, 13, 20417314221087417.

Zhang, N., Lin, J., & Chew, S. Y. (2021). Neural cell membrane-coated nanoparticles for targeted and enhanced uptake by central nervous system cells. ACS Applied Materials & Interfaces, 13(47), 55840-55850.

Marinval, N., & Chew, S. Y. (2021). Mechanotransduction assays for neural regeneration strategies : a focus on glial cells. APL Bioengineering, 5(2), 021505.

Chooi, W. H., Dong, Q., Low, J. Z. Y., Yuen, C., Chin, J. S., Lin, J., ... & Chew, S. Y. (2021). Cell membrane-coated electrospun fibers enhance keratinocyte growth through cell-type specific interactions. ACS Applied Bio Materials, 4(5), 4079-4083.

Lin, P. H., Dong, Q., & Chew, S. Y. (2021). Injectable hydrogels in stroke and spinal cord injury treatment : a review on hydrogel materials, cell–matrix interactions and glial involvement. Materials Advances, 2(8), 2561-2583.

William Ong, Nicolas Marinval, Junquan Lin, Mui Hoon Nai, Yee‐Song Chong, Coline Pinese, Sreedharan Sajikumar, Chwee Teck Lim, Charles Ffrench‐Constant, Marie E. Bechler, Sing Yian Chew (2020), 'Biomimicking Fiber Platform with Tunable Stiffness to Study Mechanotransduction Reveals Stiffness Enhances Oligodendrocyte Differentiation but Impedes Myelination through YAP‐Dependent Regulation', Small,

Kunyu Zhang, Wai Hon Chooi, Shuang Liu, Jiah Shin Chin, Aoife Murray, Dean Nizetic, Du Cheng and Sing Yian Chew (2020), 'Localized delivery of CRISPR/dCas9 via layer-by-layer self-assembling peptide coating on nanofibers for neural tissue engineering', Biomaterials, 256, pp. 120225,

U Milbreta, J Q Lin, C Pinese, W Ong, J S Chin, H Shirahama, R Mi, A Williams, M E Bechler, J Wang, C french-Constant, A Hoke, S Y Chew (2018), 'Scaffold-mediated sustained, non-viral delivery of miR-219/miR-338 promotes CNS remyelination', Molecular Therapy, 27 (2), pp. 411-423,

Na Zhang, U Milbreta, J S Chin, C Pinese, J Q Lin, H Shirahama, W Jiang, H Liu, R Mi, A Hoke, WT Wu, S Y Chew (2019), 'Biomimicking Fiber Scaffold as an Effective In Vitro and In Vivo MicroRNA Screening Platform for Directing Tissue Regeneration', Advanced Science, 6 (9), pp. 1800808,

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