Academic Profile : Faculty

NA Assoc Prof Pu Kanyi 0004rc.jpg picture
Prof Pu Kanyi
Associate Dean (Research), College of Engineering
Professor, School of Chemistry, Chemical Engineering and Biotechnology
 
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Dr. Kanyi Pu is a Professor of Biomedical Engineering in School of Chemistry, Chemical Engineering and Biotechnology (CCEB) and Lee Kong Chian School of Medicine at Nanyang Technological University. He is a Singapore National Research Foundation (NRF) Investigator, a highly cited researcher listed by Clarivate Analytics, Fellow of the Royal Society of Chemistry (FRSC), and the associate editor for ACS Applied Polymer Materials and Biomaterials Research. With a h-index of 108, he has won a number of awards for his creative work, including 2020 Biomaterials Science Lectureship Award, 2019 distinguished lectureship award from the Chemistry Society of Japan, 2018 Wiley award for contribution in bioscience, 2017 young innovator award in nanobiotechnology by Nano Research, and young investigator travel award by WMIC. He is the member of board of directors of Chinese American Society of Nanomedicine and Nanobiotechnology (CASNN). He also sits on the editorial advisory board of many top journals such as Chemical Society Reviews, Advanced Functional Materials, Biomaterials, Small, Bioconjugate Chemistry, ACS Biomaterials Science and Engineering, ACS Applied Bio Materials, Journal of Nanobiotechnology etc.
The board research objective in my group is to develop multifunctional platform technologies for understanding, detection and treatment of life-threatening diseases. Toward this goal, we will take an interdisciplinary approach that brings together organic chemistry, nanotechnology and molecular biology to synthesize functional polymers, polish their optoelectronic and biochemical properties, and shape them into smart and biocompatible nanoagents for advanced molecular imaging and amplified therapy.

(1) Molecular Imaging: Detection and monitoring of pathological processes in disease microenvironment at the molecular level for prognosis, diagnosis and therapeutic outcome assessment
(2) Chemical Biology: Design and synthesis of activatable imaging probes to uncover how reactive radical species modulate tumor metabolism, promote metastasis and angiogenesis, and foster drug resistance phenotypes
(3) Materials Science: Development of organic semiconducting nanomaterials with state-of-art imaging modalities such as photoacoustic imaging, near-infrared fluorescence imaging and bioluminescent imaging to improve imaging penetration depth and spatial resolution
(4) Biotechnology: Development of noninvasive high-throughput technologies for drug screening with a focus on real-time in vivo imaging of drug metabolism and evolution of drug-induced toxicity
 
  • Additive Manufacturing for Biological Materials (AMBM)
  • Development of COE Research Impact Framework (RIF)
  • Development of Photoacoustic Molecular Sensors
  • Molecular Optical Imaging and Early Diagnosis of Acute Kidney Injury
  • Optical Artificial Urinary Biomarkers for Next Generation Home Diagnostics
  • Tandem activatable molecular reporters for real-time longitudinal optical imaging of cancer immunotherapy
Courses Taught
CB1103 Organic Chemistry for Engineers
BG2131 Biomaterials