Academic Profile : Faculty

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Assoc Prof Melissa Jane Fullwood
Associate Chair (Students), School of Biological Sciences
Associate Professor, School of Biological Sciences
Assistant Chair (Students), School of Biological Sciences (SBS)
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Dr. Melissa J. Fullwood is a Nanyang Assistant Professor in the School of Biological Sciences in NTU, with a joint appointment as a Principal Investigator in the Cancer Science Institute of Singapore. Her lab works on understanding the roles of 3-dimensional organization of our genome in transcription regulation in cancer cells.

She completed her undergraduate degree in Biological Sciences in 2005 at Stanford University and her PhD with the National University of Singapore Graduate School for Integrative Sciences and Engineering (NGS) in 2009, at the Genome Institute of Singapore. She worked as a Lee Kuan Yew Post-doctoral Fellow in Duke-NUS Graduate Medical School. She became a Junior Principal in the Cancer Science Institute of Singapore in 2013 upon winning a National Research Foundation Fellowship, and joined School of Biological Sciences, NTU as an Assistant Professor in 2015.

She was a recipient of the Agency for Science, Technology and Research (A*STAR) National Science Scholarships, a L’Oreal-UNESCO for Women in Science National Fellowships in Singapore in 2009, and was the international winner of the GE and Science prize, as well as the A*STAR/SNAS Young Scientist Award.
3-dimensional organization of cancer genomes in transcriptional regulation
 
  • Characterization of the roles of the H3K27me3-rich genomic regions as silencers of gene expression in Myeloid Leukemias
  • Investigating the regulation of 3D genome organization using machine learning
  • Mechanisms of Progesterone Antagonism of Estrogen Action on the Endometrium
  • RNA Therapeutics against RNA m6A Methyltransferases as Cancer Therapy: Case Study in Acute Myeloid Leukemia and Multiple Myeloma