Academic Profile : Faculty

NorrisRayDunn.jpg picture
Assoc Prof Norris Ray Dunn
Associate Professor, Lee Kong Chian School of Medicine
House Tutor, Lee Kong Chian School of Medicine (LKCMedicine)
Postgraduate Tutor, Lee Kong Chian School of Medicine (LKCMedicine)
Journal Articles
(Not applicable to NIE
staff as info will be
pulled from PRDS)
Chia, C.Y., P. Madrigal, S.L.I.J. Denil, R. El-Khairi, M. Chhatriwala, M.H. Shepherd, A.T. Hattersely, L. Vallier* and N.R. Dunn*. 2019. GATA6 cooperates with EOMES/SMAD2/3 to deploy the gene regulatory network governing human definitive endoderm and pancreas formation. Stem Cell Reports 12, 57-70. (*co-Senior and corresponding author)

Trott, J.F., E.K. Tan, S. Ong, D.M. Titmarsh, S.L.I.J. Denil, M. Giam, C.K. Wong, J. Wang, M. Shboul, M. Eio, J. Cooper-White, S.M. Cool, G. Rancati, L.W. Stanton, B. Reversade and N.R. Dunn*. 2017. Long-term culture of self-renewing pancreatic progenitor cells derived from human pluripotent stem cells. Stem Cell Reports 8, 1675-1688.

Mzoughi, S., J. Zhang, D. Hequet, S.X. Teo, H. Fang, Q.R. Xing, M. Bezzi, M.K.Y. Seah, S.L.M. Ong, M.E. Shin, H. Wollmann, E.S.M. Wong, M. Al-Haddawi, C.L. Stewart, V. Tergaonkar, Y.H. Loh, N.R. Dunn, D.M. Messerschmidt and E. Guccione. 2017. PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK-ERK signaling. Nature Genetics 49, 1354-1363.

Ho, L., S.Y. Tan, S. Wee, Y. Wu, S.J. Tan, N.B. Ramakrishna, S.C. Chng, I. Szczerbinska, Y.S. Chan, S. Avery, N. Tsuneyoshi, H.H. Ng, J. Gunaratne, N.R. Dunn and B. Reversade. 2015. ELABELA is an endogenous growth factor that sustains hESC self-renewal via the PI3K/AKT pathway. Cell Stem Cell 17, 435-47.

Teo, A.K.K., N. Tsuneyoshi, E.K. Tan, S. Hoon, L.W. Stanton, C.V. Wright and N.R. Dunn*. 2015. PDX1 binds and represses hepatic genes to ensure robust pancreatic commitment in differentiating human embryonic stem cells. Stem Cell Reports 4, 578-590.

Young, T., Y. Poobalan, E.K. Tan, A. Sadasivam, S. Tao, C.Y. Lim, P. Wehner, M. Lovatt, W.S. Tein, Y. Ali, A. Borchers, K. Sampath and N.R. Dunn. 2014. The The PDZ domain protein Mutated in ColorectalCancer (Mcc) is a novel effector of non-canonical WNT signalling during convergence and extension in zebrafish. Development 141, 3505-3516

Tsuneyoshi, N., T. Sumi, A. Sadasivam, E.K. Tan, N. Nakatsuji, H. Suemori and N.R. Dunn*. 2012. The SMAD2/3corepressor SNON maintains pluripotency through selective repression of mesendodermal genes in human ES cells. Genes & Development 26, 2471-2476.

Teo, A.K.K., Y. Ali, K.Y. Wong, H. Chipperfield, A. Sadasivam, Y. Poobalan, E.K. Tan, S. Abraham, L.W. Stanton, and N.R. Dunn*. 2012. Activin A and BMP4 synergistically promote formation of definitive endoderm in human embryonic stem cells. Stem Cells 30, 631-642.

Brown, S., A. Teo, N. Hannan, C.H.H. Cho, B. Lim, L. Vardy, N.R. Dunn, M. Trotter, R. Pedersen, and L. Vallier. 2011. Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors. Stem Cells 29, 1176-85.

Teo, A.K.K., S.J. Arnold, M.W.B. Trotter, S. Brown, L.T. Ang, Z. Chng, E.J. Robertson, N.R. Dunn*, and L. Vallier*. 2011. Pluripotency factors regulate definitive endoderm specification through Eomesodermin. Genes & Development 25, 238-250. (*co-Senior and corresponding author)