Academic Profile : Faculty

Prof Anna Barron (For Web) v2.png picture
Asst Prof Barron Anna
Nanyang Assistant Professor, Lee Kong Chian School of Medicine
Journal Articles
(Not applicable to NIE
staff as info will be
pulled from PRDS)
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1. Nutma E, Fancy N, Weinert M, Tsartsalis S, Marzin MC, Muirhead RCJ, Falk I, Breur M, de Bruin J, Hollaus D, Pieterman R, Anink J, Story D, Chandran S, Tang J, Trolese MC, Saito T, Saido TC, Wiltshire KH, Beltran-Lobo P, Phillips A, Antel J, Healy L, Dorion MF, Galloway DA, Benoit RY, Amosse Q, Ceyzériat K, Badina A, Kovari E, Bendotti C, Aronica E, Radulescu CI, Wong JH, Barron AM et al., Owen D.* (2023) Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases. Nature Communications . 14: 5247.

2. Fairley L, Lai KO, Wong JH, Chong WJ, Vincent A, D’Agostino G, Wu XT, Naik RR, Jayaraman A, Langley SR, Ruedl C, Barron AM* (2023) Mitochondrial control of microglial phagocytosis by the translocator protein and hexokinase 2 in Alzheimer’s disease. Proceedings of National Academy of Sciences . 120(8): e2209177120.
Featured in the Straits Times

3. Quick JD, Silva C, Wong JH, Lim KL, Reynolds R, Barron AM , Zeng JL, Lo CH.* (2023). Lysosomal acidification dysfunction in microglia: an emerging pathogenic mechanism of neuroinflammation and neurodegeneration. Journal of Neuroinflammation , 20(1), 185.

4. Wu XT, Saito T, Saido TC, Barron AM , Ruedl C. (2021) Microglia and border-associated mouse macrophages maintain their embryonic origin during Alzheimer’s disease. ELife . 2021;10:e71879 doi.org/10.7554/eLife.71879

5. Chen Q, Lai SM, Xu S, Tan Y, Leong K, Liu D, Tan JC, Naik R, Barron AM , Adav SS, Jinmiao C, Shu C, Guan LG, Ruedl C.* (2021) Resident macrophages restrain pathological adipose tissue remodeling and protect vascular integrity in obese mice. EMBO Reports . 22(8):e52835. DOI: 10.15252/embr.202152835.

6. Fairley L, Suhara T, Ji B, Higuchi M, Barron AM* (2021) Neuroprotective effect of mitochondrial translocator protein ligand in a mouse model of tauopathy. Journal of Neuroinflammation . 18:76. https://doi.org/10.1186/s12974-021-02122-1.

7. Fairley L, Wong JH, Barron AM* (2021) Mitochondrial regulation of microglial immunometabolism in Alzheimer’s disease. Frontiers in Immunology . 12 (257): 624538. https://doi.org/10.3389/fimmu.2021.624538.

8. Barron AM* , Ji B, Fujinaga M, Zhang M-R, Suhara T, Sahara N, Aoki I, Tsukada H, Higuchi M* (2020) In vivo positron emission tomography imaging of mitochondrial abnormalities in a mouse model of tauopathy. Neurobiology of Aging . 94: 140 - 148.

9. Barron AM , Higuchi M., Hattori S., Kito S., Suhara T., Ji. B. (2020) Regulation of Anxiety and Depression by Mitochondrial translocator protein-mediated steroidogenesis: the role of neurons. Molecular Neurobiology . 58: 550–563. https://doi.org/10.1007/s12035-020-02136-5.

10. Barron AM , Ji B, Kito S, Suhara T, Higuchi M.* (2018) Steroidogenic abnormalities in translocator protein knockout mice and significance in the aging male. Biochemical Journal . 475(1):75-85.
Editors Pick of research highlights published in Biochemical Journal in 2018-2019’
Book Chapters
(Not applicable to NIE
staff as info will be
pulled from PRDS)
1. Verma NK*, Naik RR, Wong BHS, Jayaraman A, Fazil MHUT, Lim KY, Cheam MS, Yuan JCX, Ting JKY, Mamidi A, Lakshminarayanan R, Lai KO, Wong JH, Fairley LH, Vincent A, Lee CZQ, Verma R, Barron AM.* (2023) Autoimmune and Autoinflammatory Neurologic Disorders. In Translational Immunity. Elsevier.

2. Verdile G, Barron AM , Martins RN. (2018) Hormonal expression associated with Alzheimer’s disease and neurodegenerative diseases. In Neurodegeneration and Alzheimer’s Disease: The Role of Diabetes, Genetics, Hormones, and Lifestyle. Wiley.

3. Barron AM , Verdile G, Martins RN. (2008) The Role of Luteinizing Hormone in Alzheimer’s Disease. In Gonadal and Nongonadal Actions of Gonadotropins. Delhi, India: Narosa Publishing House Pvt. Ltd; pp 275-90.