Academic Profile : Faculty

marie_loh_1_2.JPG picture
Asst Prof Marie Loh Chiew Shia
Assistant Professor, Lee Kong Chian School of Medicine
Postgraduate Tutor, Lee Kong Chian School of Medicine (LKCMedicine)
Journal Articles
(Not applicable to NIE
staff as info will be
pulled from PRDS)
Selected key publications (*: equal contribution)
1. Loh M*, Zhang W*, Ng HK, …, Kooner JS*, Saleheen D*, Chambers JC*. Identification of genetic effects underlying Type 2 Diabetes in South Asian and European populations. Commun Biol 5, 329 (2022). IF: 6.27

2. Hawe JS, Wilson R, Schmid K, …, Loh M*, Heinig M*, Gieger C*, Waldenberger M*, Chambers JC*. Genetic variation influencing DNA methylation provides new insights into the molecular pathways regulating genomic function. Nature Genetics, 54(1):18-29 2022 Jan. IF: 38.33

3. Chen Y, Kassam I, Lau SH, Kooner JS, Wilson R, Peters A, Winkelmann J, Chambers JC, Chow VT, Khor CC, van Dam RM, Teo YY, Loh M*, Sim X*. Impact of BMI and waist circumference on epigenome-wide DNA methylation and identification of epigenetic biomarkers in blood: an EWAS in multi-ethnic Asian individuals. Clin Epigenetics. 2021 Oct 20;13(1):195. IF: 6.55

4. Kassam I, Tan S, Gan FF, …, Loh M.. Genome-wide identification of cis DNA methylation quantitative trait loci in three Southeast Asian populations. Human Molecular Genetics 2021 Feb 6:ddab038. IF: 4.48

5. Loh M, Zhou L, Ng HK and Chambers JC. Epigenetic disturbances in obesity and diabetes: epidemiological and functional insights. Molecular Metabolism 2019 Sep; 27S:S33-S41. IF: 6.29

6. Zhou L, Ng HK, Drautz-Moses DI, Schuster SC, Beck S, Kim C, Chambers JC, Loh M. Systematic evaluation of library preparation methods and sequencing platforms for high-throughput whole genome bisulfite sequencing. Scientific Reports 2019 Jul 17. IF: 4.53

7. Wahl S*, Drong A*, Lehne B*, Loh M*, …, Kooner JS, Grallert H, Chambers JC. Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity Nature. 2017 Jan 5;541(7635):81-86, IF: 40.14

8. Kato N*, Loh M*, Takeuchi F*, …, van der Harst P, Kooner JS, Chambers JC. Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Nature Genetics. 2015 Sep 21. IF: 38.33

9. Chambers JC*, Loh M*, Lehne B*, …, McCarthy MI, Elliott P, Kooner JS. Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study. Lancet Diabetes Endocrinol. 2015 Jul;3(7):526-34. IF: 19.74

10. Loh M, Liem N, Vaithilingam A, Lim PL, Sapari NS, Cheng CL, Yan B, Pang B, Salto-Tellez M, Yon WP, Iacopetta B, Soong R. DNA Methylation Subgroups and the CpG Island Methylator Phenotype in Gastric Cancer: A Comprehensive Profiling Approach. BMC Gastroenterol. 2014 Mar 28;14:55. doi: 10.1186/1471-230X-14-55. IF: 2.21