Academic Profile : Faculty

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Prof Lim Kah Leong
Associate Vice President (Biomedical & Life Sciences), Lee Kong Chian School of Medicine
President's Chair in Translational Neuroscience
Professor, Lee Kong Chian School of Medicine
Professor Lim Kah Leong is Associate Vice President of Research (Biomedical and Life Sciences) at the NTU President's office. He is also a President’s Chair in Translational Neuroscience. Professor Lim works closely with the Vice President of Research and Senior Vice President (Health and Life Sciences) to advance institutional initiatives for research excellence in Biomedical and Life Sciences. He was Vice Dean for Research at LKCMedicine from 2019-2023.

Professor Lim obtained his Ph.D. from the Singapore Institute of Molecular & Cell Biology in 1999. Thereafter, he did his postdoctoral training firstly at the Department of Pathology in Harvard Medical School (2000-2001), and subsequently at the Department of Neurology in Johns Hopkins University School of Medicine (2001-2002) where he worked on the topic of Parkinson’s disease with Professor Ted Dawson.

Prior to joining LKCMedicine, Professor Lim was Head of the Department of Physiology at the National University of Singapore Yong Loo Lin School of Medicine and Deputy Research Director at the National Neuroscience Institute. Professor Lim has received numerous awards including the prestigious (Singapore) President’s Science Award (Team) and the Singapore Neuroscience Association Distinguished Neuroscientist Award.
Professor Lim is an expert in the areas of neuroscience and neurodegeneration, particularly in the field of Parkinson’s Disease. With a long-term goal to elucidate the molecular events underlying Parkinson’s Disease and to effectively treat the disease, his research centres on mechanisms underlying neurodegeneration, which will reveal targets for neuroprotection. He is also developing new research technologies in the area of stem cells and neurorestoration as well as in diagnostics and neurotechnology, where he collaborates extensively with chemists, materials scientists and engineers. His laboratory uses a broad range of disease models including Drosophila, rodents, human neurons and brain organoids generated from patient-derived induced pluripotent stem cells and non-human primates (marmosets).
 
  • Centre for Human Organ Systems Emulation (CeHOrSE)
  • Engineering Scaffold-Mediated Neural Cell Therapy for Spinal Cord Injury Treatment
  • Engineering Scaffold-Mediated Neural Cell Therapy for Spinal Cord Injury Treatment (Astar)
  • Generation of Immune Evasive Cardiovascular Progenitor Cells from Cord lining-derived induced Pluripotent Stem (CLiPS) Cells
  • Human Umbilical Cord-Lining Derived Induced Pluripotent StemCells (CLiPS) as a Universal Source of Cells for Regenerative Therapy for Neurosensory Disorders
  • Neuroprotection for Parkinson’s disease – Lesson from a long-lived animal
  • Neuroprotective Strategies for Parkinson's disease
  • Novel methods of network modelling and personalised machine learning to understand and predict individual dementia using heterogeneous multi-omics data
  • Proteomic profiling of exosome molecular signatures in alpha-synuclein induced Parkinson’s disease
  • Theranostics approach for the treatment of Parkinson’s Disease
  • Therapeutic and biomarker discovery for lysosomal acidification dysfunction in Alzheimer’s disease and related dementias