Academic Profile

Dr Sunny Wong is a clinician-scientist and an Associate Professor at the Lee Kong Chian School of Medicine, Nanyang Technological University Singapore. He received his MBChB with Honors at the Chinese University of Hong Kong, and his PhD in University of Oxford on human genetics and infectious diseases. He completed his clinical training in internal medicine and gastroenterology in the Prince of Wales Hospital Hong Kong. His main research interest is on gut microbiome, investigating the host-microbe interaction in digestive and metabolic diseases, and exploring this for discovery of novel biomarkers and therapeutics. He has won several awards, including the Asia Pacific Digestive Week Emerging Leaders Lectureship (2021), the Hong Kong College of Physicians Sir David Todd Lectureship (2020), the Lo Ying Shek Chi Wai Foundation Meritorious Research Award (2020), and the Croucher Foundation Award (2014). He has published over 150 peer-reviewed articles including papers in Nature Genetics, Gastroenterology and Gut, and is currently an Associate Editor for the Journal of Gastroenterology and Hepatology.
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Assoc Prof Sunny Wong
Associate Professor of Nutrition, Digestion and Metabolism, Lee Kong Chian School of Medicine
Associate Professor, Lee Kong Chian School of Medicine

Microbiome; Nutrition; Digestive Diseases; Metabolic Syndrome; Obesity
 
  • Wong SH, Yu J. Gut microbiota in colorectal cancer: Mechanisms of action and clinical applications. Nat Rev Gastroenterol Hepatol 2019;16(11):690-704. doi: 10.1038/s41575-019-0209-8

  • Wong SH, Zhao L, Zhang X, Nakatsu G, Han J, Xu W, Xiao X, Kwong TNY, Tsoi H, Wu WKK, Zeng B, Chan FKL, Sung JJY, Wei H, Yu J. Gavage of fecal samples from patients with colorectal cancer promotes intestinal carcinogenesis in germ-free and conventional mice. Gastroenterology 2017;153(6):1621-33 e6. doi: 10.1053/j.gastro.2017.08.022

  • Wong SH, Kwong TNY, Chow TC, Luk AKC, Dai RZW, Nakatsu G, Lam TYT, Zhang L, Wu JCY, Chan FKL, Ng SSM, Wong MCS, Ng SC, Wu WKK, Yu J, Sung JJY. Quantitation of faecal fusobacterium improves faecal immunochemical test in detecting advanced colorectal neoplasia. Gut 2017;66(8):1441-48. doi: 10.1136/gutjnl-2016-312766

  • Kwong TNY, Wang X, Nakatsu G, Chow TC, Tipoe T, Dai RZW, Tsoi KKK, Wong MCS, Tse G, Chan MTV, Chan FKL, Ng SC, Wu JCY, Wu WKK, Yu J, Sung JJY, Wong SH. Association between bacteremia from specific microbes and subsequent diagnosis of colorectal cancer. Gastroenterology 2018;155(2):383-90 e8. doi: 10.1053/j.gastro.2018.04.028

  • Ho J, Dai RZW, Kwong TNY, Wang X, Zhang L, Ip M, Chan R, Hawkey PMK, Lam KLY, Wong MCS, Tse G, Chan MTV, Chan FKL, Yu J, Ng SC, Lee N, Wu JCY, Sung JJY, Wu WKK, Wong SH. Disease burden of Clostridium difficile infections in adults, Hong Kong, China, 2006-2014. Emerg Infect Dis 2017;23(10):1671-79. doi: 10.3201/eid2310.170797

  • Kong KY, Kwong TNY, Chan H, Wong K, Wong SSY, Chaparala AP, Chan RCY, Zhang L, Sung JJY, Yu J, Hawkey PM, Ip M, Wu WKK, Wong SH. Biological characteristics associated with virulence in Clostridioides difficile ribotype 002 in Hong Kong. Emerg Microbes Infect 2020;9(1):631-38. doi: 10.1080/22221751.2020.1739564

  • Wong SH, Ip M, Hawkey PM, Lo N, Hardy K, Manzoor S, Hui WW, Choi KW, Wong RY, Yung IM, Cheung CS, Lam KL, Kwong T, Wu WK, Ng SC, Wu JC, Sung JJ, Lee N. High morbidity and mortality of Clostridium difficile infection and its associations with ribotype 002 in Hong Kong. J Infect 2016;73(2):115-22. doi: 10.1016/j.jinf.2016.05.010

  • Wong SH, Gochhait S, Malhotra D, Pettersson FH, Teo YY, Khor CC, Rautanen A, Chapman SJ, Mills TC, Srivastava A, Rudko A, Freidin MB, Puzyrev VP, Ali S, Aggarwal S, Chopra R, Reddy BS, Garg VK, Roy S, Meisner S, Hazra SK, Saha B, Floyd S, Keating BJ, Kim C, Fairfax BP, Knight JC, Hill PC, Adegbola RA, Hakonarson H, Fine PE, Pitchappan RM, Bamezai RN, Hill AV, Vannberg FO. Leprosy and the adaptation of human toll-like receptor 1. PLoS Pathog 2010;6(7):e1000979. doi: 10.1371/journal.ppat.1000979

  • Wong SH, Hill AV, Vannberg FO, India-Africa-United Kingdom Leprosy Genetics Consortium. Genomewide association study of leprosy. N Engl J Med 2010;362(15):1446-7; author reply 47-8. doi: 10.1056/NEJMc1001451

  • Thye T, Vannberg FO, Wong SH, Owusu-Dabo E, Osei I, Gyapong J, Sirugo G, Sisay-Joof F, Enimil A, Chinbuah MA, Floyd S, Warndorff DK, Sichali L, Malema S, Crampin AC, Ngwira B, Teo YY, Small K, Rockett K, Kwiatkowski D, Fine PE, Hill PC, Newport M, Lienhardt C, Adegbola RA, Corrah T, Ziegler A, African TBGC, Wellcome Trust Case Control C, Morris AP, Meyer CG, Horstmann RD, Hill AVS. Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2. Nat Genet 2010;42(9):739-41. doi: 10.1038/ng.639