Academic Profile : Faculty

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Assoc Prof Nagaendran Kandiah
Associate Professor of Neuroscience, Lee Kong Chian School of Medicine
Associate Professor, Lee Kong Chian School of Medicine
Associate Professor Nagaendran Kandiah is the Director of the Dementia Research Centre at LKC-NTU School of Medicine. He is a senior neurologist with specialization in cognitive neurology and vascular neurology. He also holds an appointment as Clinician Scientist with National Medical Research Council.
My research focuses on developing novel biomarkers and interventional strategies for mild cognitive impairment and dementia. My lab uses a combination of fluid biomarkers, neuroimaging and neurocognitive panels in investigating Alzheimer's disease, vascular dementia and other related neurodegenerative diseases.
 
  • Cerebrovascular Health, Adult Learning, Resilience and Mechanisms: CHARM Study
  • Comprehensive Digital-Fluid Biomarker Platform for the Detection and Classification of Mild Cognitive Impairment (DECODE)
  • Dementia Research Centre Singapore (LKC-NNI-A*STAR)
  • Dynamic Metal-Enhanced Fluorescence Microarray for Ultrasensitive Detection of Neurodegenerative Disease Biomarkers
  • Early detection of mild cognitive impairment (MCI) through a novel digital assessment
  • Elucidating brain structure-function interaction implications in brain diseases via explainable AI
  • Insights into the Pathobiology of Cerebral White Matter Disease in Mild Cognitive Impairment and Prevention Strategies with Pharmacological and Digital-Artificial Intelligence
  • Molecular underpinning of cerebrovascular dysfunctions in vascular dementia
  • Novel methods of network modelling and personalised machine learning to understand and predict individual dementia using heterogeneous multi-omics data
  • Novel MRI Toolbox to Classify and Predict Asian Mild Cognitive Impairment
  • Pathobiology of Frailty in Mild Cognitive Impairment
  • Prevention of and Biomarkers for Vascular Cognitive Impairment - The SINgapore GERiatric intervention study to reduce cognitive decline and physical frailty (SINGER) Study, biomarker and health service research analyses (Theme 1)
  • Protecting Our Wisdom, Enhancing Resilience to Dementia (POWERD)
  • ReCOGnAIze – an app to aid clinicians in the diagnosis and prognostication of Vascular Mild Cognitive Impairment (VMCI)
  • Theranostics approach for the treatment of Parkinson’s Disease
  • Therapeutic and biomarker discovery for lysosomal acidification dysfunction in Alzheimer’s disease and related dementias