Academic Profile : Faculty
Prof Kanaga Sabapathy
Chair, School of Biological Sciences
Professor, School of Biological Sciences
Journal Articles
(Not applicable to NIE
staff as info will be
pulled from PRDS)
(Not applicable to NIE
staff as info will be
pulled from PRDS)
“Hypoxia-inducible TAp73 regulates the angiogenic transcriptome and supports tumorigenesis”.
Dulloo I, Phang BH, Othman R, Tan SY, Vijayaraghavan A, Goh LK, Martin-Lopez M, Marques MM, Li CW, Wang DY, Marin MC, Xian W, McKeon F and Sabapathy K.
Nature Cell Biol. 2015. 17(4):511-523.
“Amino-terminal p53 mutations lead to expression of apoptosis proficient p47 and prognosticate better survival, but predispose to tumorigenesis”.
Phang BH, Othman R, Bougeard G, Chia RH, Frebourg T, Tang CL, Cheah PY, Sabapathy K.
Proc Natl Acad Sci U S A. 2015. 112(46):6349-6358.
“Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others”.
Sabapathy K, Lane DP.
Nature Review Clinical Oncology. 2018. 15(1):13-30.
“Novel tools for precision medicine - monoclonal antibodies against specific p53 hot-spot mutants”.
Hwang LA, Phang BH, Liew OW, Iqbal J, Koh XH, Koh XY, Othman R, Xue Y, Richards AM, Lane DP*, Sabapathy K*.
Cell Reports. 2018. 22:299-312.
“Context-dependent AMPK activation distinctly regulates TAp73 stability and transcriptional activity”.
Li D, Dulloo I, Sabapathy K.
Signal Transduct Target Ther. 2018. 3:20. eCollection 2018
“Cancer therapeutic targeting using mutant-p53-specific siRNAs”.
Ubby I, Krueger C, Rosato R, Qian W, Chang J, Sabapathy K.
Oncogene. 2019. 38:3415-3427.
“Functional interaction between macrophages and hepatocytes dictate the outcome of liver fibrosis.”
Xie M, Chia RH, Li D, Teo FX, Krueger C, Sabapathy K.
Life Sci Alliance. 2021 4(4):e202000803.
“EPLIN-β is a novel substrate of ornithine decarboxylase antizyme 1 and mediates cellular migration.”
Li D, Neo SP, Gunaratne J, Sabapathy K.
J Cell Sci. 2023 136(12):jcs260427
“JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1.”
Tabanifar B, Moorthy A, Tsai HH, Kannan S, Verma CS, Sabapathy K.
Cell Rep. 2023 42(9):113123
“Adipose-enriched peri-tumoral stroma, in contrast to myofibroblast-enriched stroma, prognosticates poorer survival in breast cancers.”
Lau HSH, Tan VKM, Tan BKT, Sim Y, Quist J, Thike AA, Tan PH, Pervaiz S, Grigoriadis A, Sabapathy K.
NPJ Breast Cancer. 2023 20;9(1):84
Dulloo I, Phang BH, Othman R, Tan SY, Vijayaraghavan A, Goh LK, Martin-Lopez M, Marques MM, Li CW, Wang DY, Marin MC, Xian W, McKeon F and Sabapathy K.
Nature Cell Biol. 2015. 17(4):511-523.
“Amino-terminal p53 mutations lead to expression of apoptosis proficient p47 and prognosticate better survival, but predispose to tumorigenesis”.
Phang BH, Othman R, Bougeard G, Chia RH, Frebourg T, Tang CL, Cheah PY, Sabapathy K.
Proc Natl Acad Sci U S A. 2015. 112(46):6349-6358.
“Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others”.
Sabapathy K, Lane DP.
Nature Review Clinical Oncology. 2018. 15(1):13-30.
“Novel tools for precision medicine - monoclonal antibodies against specific p53 hot-spot mutants”.
Hwang LA, Phang BH, Liew OW, Iqbal J, Koh XH, Koh XY, Othman R, Xue Y, Richards AM, Lane DP*, Sabapathy K*.
Cell Reports. 2018. 22:299-312.
“Context-dependent AMPK activation distinctly regulates TAp73 stability and transcriptional activity”.
Li D, Dulloo I, Sabapathy K.
Signal Transduct Target Ther. 2018. 3:20. eCollection 2018
“Cancer therapeutic targeting using mutant-p53-specific siRNAs”.
Ubby I, Krueger C, Rosato R, Qian W, Chang J, Sabapathy K.
Oncogene. 2019. 38:3415-3427.
“Functional interaction between macrophages and hepatocytes dictate the outcome of liver fibrosis.”
Xie M, Chia RH, Li D, Teo FX, Krueger C, Sabapathy K.
Life Sci Alliance. 2021 4(4):e202000803.
“EPLIN-β is a novel substrate of ornithine decarboxylase antizyme 1 and mediates cellular migration.”
Li D, Neo SP, Gunaratne J, Sabapathy K.
J Cell Sci. 2023 136(12):jcs260427
“JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1.”
Tabanifar B, Moorthy A, Tsai HH, Kannan S, Verma CS, Sabapathy K.
Cell Rep. 2023 42(9):113123
“Adipose-enriched peri-tumoral stroma, in contrast to myofibroblast-enriched stroma, prognosticates poorer survival in breast cancers.”
Lau HSH, Tan VKM, Tan BKT, Sim Y, Quist J, Thike AA, Tan PH, Pervaiz S, Grigoriadis A, Sabapathy K.
NPJ Breast Cancer. 2023 20;9(1):84