Please use this identifier to cite or link to this item:
https://hdl.handle.net/10356/79628
Title: | Nanoporous carbon as a sensing platform for DNA detection : the use of impedance spectroscopy for hairpin-DNA based assay | Authors: | Poh, Hwee Ling Bonanni, Alessandra Pumera, Martin |
Keywords: | DRNTU::Science::Chemistry::Biochemistry | Issue Date: | 2012 | Source: | Poh, H. L., Bonanni, A., & Pumera, M. (2012). Nanoporous carbon as a sensing platform for DNA detection: The use of impedance spectroscopy for hairpin-DNA based assay. RSC Advances, (2), 1021-1024. | Series/Report no.: | RSC advances | Abstract: | Nanoporous carbons represent well defined materials with large surface area, defined porosity, high electrical conductivity and fast heterogeneous electron transfer rates. These materials are seldom used for sensing and even more rarely for biosensing. We for the first time show the application of nanoporous carbon using electrochemical impedance spectroscopy technique to detect DNA hybridization and polymorphism. Our findings demonstrated the proof of concept of using nanoporous carbon in nucleic acid analysis, being able to detect the presence of a single nucleotide polymorphism. | URI: | https://hdl.handle.net/10356/79628 http://hdl.handle.net/10220/10029 |
DOI: | 10.1039/C1RA00812A | Schools: | School of Physical and Mathematical Sciences | Rights: | © 2012 The Royal Society of Chemistry. This paper was published in RSC Advances and is made available as an electronic reprint (preprint) with permission of The Royal Society of Chemistry. The paper can be found at the following official DOI: [http://dx.doi.org/10.1039/C1RA00812A]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
Appears in Collections: | SPMS Journal Articles |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Nanoporous carbon as a sensing platform for DNA detection.pdf | 679.4 kB | Adobe PDF | View/Open |
SCOPUSTM
Citations
20
13
Updated on Mar 13, 2024
Web of ScienceTM
Citations
20
12
Updated on Oct 27, 2023
Page view(s) 10
764
Updated on Mar 18, 2024
Download(s) 10
374
Updated on Mar 18, 2024
Google ScholarTM
Check
Altmetric
Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.