Ultrasensitive colorimetric DNA detection using a combination of rolling circle amplification and Nicking Endonuclease-Assisted Nanoparticle Amplification (NEANA)
Author
Xu, Wei
Xie, Xiaoji
Li, Dawei
Yang, Zhaoqi
Li, Tianhu
Liu, Xiaogang
Date of Issue
2012School
School of Physical and Mathematical Sciences
Abstract
A combination of rolling circle amplification and nicking endonuclease-assisted nanoparticle amplification (NEANA) is used for the rapid, colorimetric detection of DNA. The integration of rolling circle amplification into the NEANA approach allows for detection of oligonucleotides with arbitrary sequences at ultralow concentrations.
Type
Journal Article
Series/Journal Title
Small
Rights
© 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Collections
http://dx.doi.org/10.1002/smll.201200263
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