Dehydrogenative amide synthesis : azide as a nitrogen source
Hong, Soon Hyeok
Date of Issue2012
School of Physical and Mathematical Sciences
A new atom-economical strategy to amide linkage from an azide and alcohol liberating hydrogen and nitrogen was developed with an in situ generated ruthenium catalytic system. The reaction has broad substrate generality including diols for the synthesis of cyclic imides.
© 2012 American Chemical Society.