dc.contributor.authorLv, Hui
dc.contributor.authorTiwari, Bhoopendra
dc.contributor.authorMo, Junming
dc.contributor.authorXing, Chong
dc.contributor.authorChi, Robin Yonggui
dc.date.accessioned2013-06-25T02:49:55Z
dc.date.available2013-06-25T02:49:55Z
dc.date.copyright2012en_US
dc.date.issued2012
dc.identifier.citationLv, H., Tiwari, B., Mo, J., Xing, C., & Chi, Y. R. (2012). Highly Enantioselective Addition of Enals to Isatin-Derived Ketimines Catalyzed by N-Heterocyclic Carbenes: Synthesis of Spirocyclic γ-Lactams. Organic Letters, 14(21), 5412-5415.en_US
dc.identifier.issn1523-7060en_US
dc.identifier.urihttp://hdl.handle.net/10220/10587
dc.description.abstractAn N-heterocyclic carbene (NHC)-catalyzed annulation reaction of isatin N-Boc ketimines and enals is developed for the synthesis of spirocyclic oxindole-γ-lactams bearing one quaternary chiral center in good yields and excellent stereoselectivities (up to >20:1 dr and 99% ee).en_US
dc.language.isoenen_US
dc.relation.ispartofseriesOrganic lettersen_US
dc.rights© 2012 American Chemical Society.en_US
dc.titleHighly enantioselective addition of enals to isatin-derived ketimines catalyzed by N-heterocyclic carbenes : synthesis of spirocyclic γ-lactamsen_US
dc.typeJournal Article
dc.contributor.schoolSchool of Physical and Mathematical Sciencesen_US
dc.identifier.doihttp://dx.doi.org/10.1021/ol302475g
dc.identifier.rims173627


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