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Title: Copper-catalyzed aerobic intramolecular carbo- and amino-oxygenation of alkynes for synthesis of azaheterocycles
Authors: Toh, Kah Kah
Sanjaya, Stephen
Sahnoun, Sophian
Chong, Sin Yee
Chiba, Shunsuke
Issue Date: 2012
Source: Toh, K. K., Sanjaya, S., Sahnoun, S., Chong, S. Y., & Chiba, S. (2012). Copper-Catalyzed Aerobic Intramolecular Carbo- and Amino-Oxygenation of Alkynes for Synthesis of Azaheterocycles. Organic Letters, 14(9), 2290-2292.
Series/Report no.: Organic letters
Abstract: A synthetic method of highly substituted quinolines has been developed from N-(2-alkynylaryl)enamine carboxylates under Cu-catalyzed aerobic conditions via intramolecular carbo-oxygenation of alkynes. This strategy was further applied for N-alkynylamidines for amino-oxygenation of alkynes, leading to imidazole and quinazoline derivatives.
ISSN: 1523-7060
DOI: 10.1021/ol3007106
Rights: © 2012 American Chemical Society.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

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