Copper-catalyzed aerobic spirocyclization of biaryl-N-H-imines via 1,4-aminooxygenation of benzene rings
Tnay, Ya Lin
Chua, Yi Yuan
Date of Issue2012
School of Physical and Mathematical Sciences
A synthetic method of azaspirocyclohexadienones has been developed through copper-catalyzed aerobic spirocyclization of biaryl-N-H-imines prepared by the reaction of biarylcarbonitriles and Grignard reagents.
© 2012 American Chemical Society.