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      Copper-catalyzed aerobic spirocyclization of biaryl-N-H-imines via 1,4-aminooxygenation of benzene rings

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      Author
      Tnay, Ya Lin
      Chen, Cheng
      Chua, Yi Yuan
      Zhang, Line
      Chiba, Shunsuke
      Date of Issue
      2012
      School
      School of Physical and Mathematical Sciences
      Abstract
      A synthetic method of azaspirocyclohexadienones has been developed through copper-catalyzed aerobic spirocyclization of biaryl-N-H-imines prepared by the reaction of biarylcarbonitriles and Grignard reagents.
      Type
      Journal Article
      Series/Journal Title
      Organic letters
      Rights
      © 2012 American Chemical Society.
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      • SPMS Journal Articles
      http://dx.doi.org/10.1021/ol301583y
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