A CuBr-mediated aerobic reaction of 2-alkynylbenzaldehydes and primary amines : synthesis of 4-bromoisoquinolones
Too, Pei Chui
Date of Issue2012
School of Physical and Mathematical Sciences
A method for synthesis of 4-bromoisoquinolones has been developed starting from 2-alkynylbenzaldehydes and primary amines mediated by CuBr under an O2 atmosphere, where CuBr plays multiple roles to facilitate the present reactions.
© 2012 The Royal Society of Chemistry.