dc.contributor.authorZhao, Huaiqing
dc.contributor.authorOng, Wei Qiang
dc.contributor.authorZhou, Feng
dc.contributor.authorFang, Xiao
dc.contributor.authorChen, Xueyuan
dc.contributor.authorLi, Sam F. Y.
dc.contributor.authorSu, Haibin
dc.contributor.authorCho, Nam-Joon
dc.contributor.authorZeng, Huaqiang
dc.date.accessioned2013-07-10T06:12:15Z
dc.date.available2013-07-10T06:12:15Z
dc.date.copyright2012en_US
dc.date.issued2012
dc.identifier.citationZhao, H., Ong, W. Q., Zhou, F., Fang, X., Chen, X., Li, S. F. Y., et al. (2012). Chiral crystallization of aromatic helical foldamers via complementarities in shape and end functionalities. Chemical Science, 3(6), 2042-2046.
dc.identifier.urihttp://hdl.handle.net/10220/11105
dc.description.abstractBiomolecules such as α-helices are exclusively right-handed without contamination by their left-handed counterparts. Within the abiotic world, chiral or external perturbations have to be applied to the abiotic helical foldamers or polymers to control and bias their helical screw sense. Otherwise, it is not possible to separate racemic helical foldamers composed of achiral building blocks. By designing two complementary “sticky” groups, incorporating them into the ends of helical pentamers and taking advantage of the energetically more favored full overlap, which involves helical backbones, we succeeded in demonstrating, for the first time, a spontaneous resolution of racemic helices into their enantiopure single-handed helical forms via chiral crystallization without the use of chiral auxiliary or external stimuli.en_US
dc.language.isoenen_US
dc.relation.ispartofseriesChemical scienceen_US
dc.rights© 2012 The Royal Society of Chemistry.en_US
dc.titleChiral crystallization of aromatic helical foldamers via complementarities in shape and end functionalitiesen_US
dc.typeJournal Article
dc.contributor.schoolSchool of Materials Science and Engineeringen_US
dc.identifier.doihttp://dx.doi.org/10.1039/c2sc20219k


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