dc.contributor.authorWang, Yingqi
dc.date.accessioned2013-07-12T04:24:37Z
dc.date.available2013-07-12T04:24:37Z
dc.date.copyright2013en_US
dc.date.issued2013
dc.identifier.citationWang, Y. (2013, March). Chemical Synthesis of Cyclotide from the Medicinal Plant Clitoria ternatea. Presented at Discover URECA @ NTU poster exhibition and competition, Nanyang Technological University, Singapore.en_US
dc.identifier.urihttp://hdl.handle.net/10220/11310
dc.description.abstractCyclotides are a special class of ultrastable peptides which possess a cyclized backbone and three disulfide bridges. They display many bioactivities and are attractive targets for drug discovery. The medicinal plant Clitoria ternatea contains a high abundance cyclotides, named as cliotides (cT, which have been shown to constitute the active ingredients of C. ternatea. cT19 is one of the cliotides that showed strong antibacterial and immunomodulatory activities. Native cT19 yield from conventional extracting methods is relatively low and it is difficult to separate cT19 from its deaminated form cT19a. With the recent understanding of cT19’s structure and amino acid sequence, chemical synthesis of cT19 is made possible. [2nd Award]en_US
dc.language.isoenen_US
dc.rights© 2013 The Author(s).en_US
dc.subjectCyclotide
dc.subjectCyclization
dc.titleChemical synthesis of cyclotide from the medicinal plant clitoria ternateaen_US
dc.typeStudent Research Poster
dc.contributor.schoolSchool of Biological Sciencesen_US
dc.contributor.supervisorSze Siu Kwanen_US
dc.description.degreeStudent Research Posteren_US


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